Metoprolol half life

Common Questions and Answers about Metoprolol half life

toprol

If you take more than one in a 24 hour period, the effect of the drug is additive due to its long half life. Please be careful!
pills of each medication, you are loosing a great deal of the latter drug's effectiveness as the day wears on. The half life of Metoprolol Tartrate is only 3-7 hours. So you must take it at least twice a day for it to be effective the entire 24 hour period. Also 25mg., once a day is a a very small dose. I'm currently on 75mg as a maintenance doseage, and have been as high as 200mg. Just something to keep in mind.
Just to show I under stand at 12 hours the 12 hour half life is at half strength while an 8 hour half life is close to 3/8th strength at 12 hours. - off the "top of the head"... sounds about right. How do we beat this???? I find the fact that I occasionally forget to take my medications sort of resets my residual levels to near zero...
may hit you harder than someone,with more body mass. Also remember that Metoprolol tartrate has a half life of about 6 hours, meaning every 6 hours or so, your body metabolizes the dose to 50% of the original amount. So 25 halves to 12, then halves to 6, then to 3mg after 18 hours. You mention ablation in your profile. It could be a good way to get rid of it forever. A lot of folks here along with myself have hadn't done. Penn has sooe great docs.
Yes... You did tell me that. But i chose to take my drs orders instead - mostly bc as someone who constantly monitors my Bp and hr, I don't find it necessary to take twice a day. My heart rate stats around 70 and my Bp stays around 100/70 all day, I find no need to introduce even more of a drug into my body when I've been on the metrication for quite some time with normal readings when only taking it once every 24 hr....
They all make me tired, some of them are worse and the Bisoprolol and Metoprolol are the worse for me in term of side-effects. The half-life of the Metoprolol is between 3 to 7 hours... some people are fast metabolizer and the effect will not last 7 hours and the drug will tend to not accumulate that much in the body and blood... I'm a fast metabolizer and with the Metoprolol it's even faster. I wake up around 7 AM and take 12.
I took 2 different versions of metoprolol, Toprol (metoprolol tartrate) and Toprol XL (metoprolol succinate). The second one is the extended release version. Toprol made my symtoms worse but Toprol XL worked fairly well in controlling my conditions, PVC's and PSVT. I was taking 50 mg a day in both cases. The only thing that affected me was a slight feeling of dizziness at times and some mental fatigue.
My interest in Atenolol was more than the half-life of the medication. As you may have read my experience so far confirms the Atenolol is longer lasting in my body... only one sample, others may get different results.
Here's the question- I am wondering if these PVC's and PAC's that I have been experiencing in the past 2 months have to do with suddenly stopping the metoprolol that I was on for my high blood pressure. I don't recall ever getting them before and now they occurring constantly..I was taking metoprolol 25 mg twice a day and then my dr discontinued it because I found out that I was pregnant. Now I am taking something else for the blood pressure that is safe to take in pregnancy.
Do you take any type of Beta Blocker for your palps? Metoprolol (Toprol) made my hair fall out BIG TIME. The hair loss is starting to slow now, 2 months after discontinuing the beta blocker....
By the way, you can compare similar weights of Metoprolol Tartrate and the time release version called Metoprolol Succicate if you consider the longer half life of the latter version.
Metoprolol has a relatively short half life of 3 to 7 hours. In other words, when you take it, its medicinal benefit begins to lessen rather quickly. By taking it only once a day, you get a spike followed by a rapid lessening of its effect. People taking Metoprolol Tartrate usually take if twice a day to maintain a relatively stable level of the drug in their system. Another thing I wanted to point out is your dosage is extremely low. Body mass could play a factor on your dose.
Not the answer/help you're looking for, but I add my data point saying I've taken Toprol and Metoprolol in medium to high dose and have never had a chocking sensation. I do not know anything about Digoxin. If the chocking has not stopped with your discontinuation of Metoprolol I'd say it has/had nothing to do with the chocking.
Metoprolol 25 mg. Does it make a difference in what I'm taking, wether I can cut in half or not? The PA knows what I am taking and he told me just to cut it.
The half life of metoprolo is 3-4 hours. Meaning the drug reamaining in your system is reduced by 1/2 every 3-4 hours. The duration of it's effects is 13-19 hours. Get out your calculator and do the math. You took a very small dose for a very short time, so you should be close to having none left in your body. If you are still "feeling" effects after your "withdrawal," call your doctor and let them know. Not everybody metabolizes at the same rate.
I always try to look at the glass as being half full and not half empty. Whenever faced with something bad, I try to find the good. Believe me, it took me a long time to get here. I was always planning the next pity party for myself. But one day, I just got up and decided to roll with the punches ,whatever they may be. For now, make sure that you drink plenty of water, get a good night sleep and see what tomorrow holds. I'll say a prayer for you.
It's instantaneous. Metoprolol Tartrate has a relatively short half-life. That's why you have to take it twice a day. I was told by my EP to stop it immedately, and that it wasn't necessary to gradually reduce it. this was prior to my cardiac ablation for SVT. But, do as instructed by you physician. I take 75mg a day, and am totally accustomed to it. Your body balances itself within a few weeks. I had dosages up to 200mg per day. That, I had a hard time with.
I am about to begin withdrawal of 50mg Metoprolol after 5 years addictions to it for blood pressure only. No heart issues. It has been used with 5mg Norvase - Calcium Channel Blocker. PCP's instructions are: 1. Stop the Norvase for 20 days to see if BP spikes. If not then proceed to: 2. Reduce from 50mg of Metoprolol twice a day to 25mg twice a day for one week. 3. Then, 1/2 a 25mg tab twice a day for one week. There was the expectation that there could or would be BP spikes. WHY?!
I'm a 46 year old male with a long (15-20 year) history of migraines, they have been gradually getting worse over time. I have been unable to work for the last year and a half, and have been bedridden for the last year due to a severe headache. The headache has not gone away at all during that time. Five years ago I had a bad stretch that I was off for about a year but not necessarily bedridden the entire time. The rest of the time I experienced what may be considered regular bad migraines.
You may have seen some of your darkest days. Perhaps you reached the very depths of despair while battling opiate addiction and or dependency. But there is hope that you can recover fully. Opiate abuse and addiction can wreck lives. It can take hold of you both physically and mentally with a grip so powerful you may do things you never thought you would out of desperation. It can cause you to steal, lie, cheat and dishonor yourself and those you love.
Took my metoprolol half tablet at 10 pm last night as usual. It never did feel like it did anything. Maybe it was a bogus pill. I had tachycardia, palpitations, irregular hearbeat on and off all night. Kept waking up suddenly out of breath. By 4:30 am I was so exhausted I could barely lift my head. I felt like all the life was draining out of me. Ken took my pulse and said it was very fast and thready. Told me to take another dose of metoprolol. I did. One hour later I felt normal again.
Best to check with your doctor... I don't know your specific medicine, but in the case of a beta blocker I have chosen to take the the regular release at 1/2 does level rather than the slow release full dose once a day. I did this for two reasons: regular release available in a very inexpensive generic version (Atenelol or Metoprolol), and two I have more confidence in getting medicated 24/7 as one each 12 hours I give it a boost.
Hi Brooke, I have a call into the cardiologist. I have been plagued with palpitations most of my life. I am very healthy, exercise all the time and weight is fine. I have just had a bout over the past two weeks with hundreds of skipped/fluttering beats. I've eliminated morning caffine and have wine occasionally. I did take my BP and it is 146/83. The added does of beta blocker isn't working. They will probably need to adjust meds.....thanks for your support.
I requested the change because the atenolol has a longer half life than regular release Metop. It is my experience after about two months on atenolol that it lowers my HR more, not what you are after. But that is only one data point not necessarily what you will experience. If you do not have any dizziness from the low resting HR it should be good. There is no doubt the beta blocker is causing the lower HR.
It is best taken in divided doses. It has a short half-life, therefore must be taken at least twice daily and as a slow-release preparation preferably. Hence it is advisable to take it 25mg twice a day instead of 50mg once a day. Hope this helps. The answer is based on information provided. Exact advice is not possible without a proper examination and investigations. You are requested to consult your Doctor. Take care and keep us posted.
] Ouch, when I asked to move from the slow release BB to normal BB, Metoprolol, to save money I had no idea the half life is so short. If I understand half life that says in 8 hours my medication level is to 25% and at 12 hours (2 half lives) down to 12.5% almost the same as empty. I take every 12 hours, approximately. I'll ask my cardiologist about Antenolol, maybe it will reduce my dreaming problems too. I take CCB to lower AFib driven high HR.
No caffine or very little I mix my coffee half and half. 4. excersize couple times a week. 5. My cardiologist told me that in his opinion it is a proven fact that taking omega 3 fish oil suppliments can prevent and sometimes cure a- fib. Although it is not fda proven. 6. Stop drinking wine a liquor completely! Beer is ok but not dark or wheat Bud light works for me DONT DRINK EXCESSIVE more than two nights in a row. 7. Get good night sleep if possible. 8.
I don't recognize the brand names, Toprolol is the only brand name I have taken, then it was to the low cost generic versions of Toprolol (Metoprolol) and later at my request to Atenolol. If you take a med only once a day it should be a slow release, even Atenolol has a half life of only 12 hours max. I may be digressing. I agree with your question: I believe less is more/better when it comes to medication. But, the change may have medical reasons you have not identified.
The nurse finally told me to break the pill in half and take half in the morning and half at night. That worked a little better. I ended up eventually on Atenolol which I have taken for 6 years. I take it in divided doses, as my bp or hr goes up or down. If my hr and bp are too low, I delay a dose. But I never just skip it. So I might take between 1-1/2 tablets over the day, sometimes 2 pills. I don't think you're supposed to just stop it.
I think of Metoprolol as the Tic-Tac of beta blockers. Both Metoprolol Succinate (which you're on) and Metoprolol Tartrate (which I'm on) are easily tolerated by most people. A common side effect is the slowing of pulse, and a lowering of blood pressure. You may have to take a few weeks for your body to be accustomed to the medicine, and you may feel a bit washed out. 25mg is a very low dose. I'm on 75mg, and have been as high as 200mg. Dosages can be as high as 400mg per day.
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