Metoprolol half life

Common Questions and Answers about Metoprolol half life

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1423357 tn?1511085442 Just to show I under stand at 12 hours the 12 hour half life is at half strength while an 8 hour half life is close to 3/8th strength at 12 hours. - off the "top of the head"... sounds about right. How do we beat this???? I find the fact that I occasionally forget to take my medications sort of resets my residual levels to near zero...
Avatar n tn ] Ouch, when I asked to move from the slow release BB to normal BB, Metoprolol, to save money I had no idea the half life is so short. If I understand half life that says in 8 hours my medication level is to 25% and at 12 hours (2 half lives) down to 12.5% almost the same as empty. I take every 12 hours, approximately. I'll ask my cardiologist about Antenolol, maybe it will reduce my dreaming problems too. I take CCB to lower AFib driven high HR.
Avatar f tn Adenosine is very short acting with a half life of only seconds, so I really doubt it would have long standing side effects, but I am not a doctor.
Avatar n tn you won't be on a time release with standard metoprolol that is why you need to take it twice a day. I don't know why you have to cut in in half, Wal-Mart has generic metoprolol in 25mg tablets for $4.
Avatar m tn No caffine or very little I mix my coffee half and half. 4. excersize couple times a week. 5. My cardiologist told me that in his opinion it is a proven fact that taking omega 3 fish oil suppliments can prevent and sometimes cure a- fib. Although it is not fda proven. 6. Stop drinking wine a liquor completely! Beer is ok but not dark or wheat Bud light works for me DONT DRINK EXCESSIVE more than two nights in a row. 7. Get good night sleep if possible. 8.
Avatar f tn The half-life of a drug is how long it takes for half of it to be eliminated from the bloodstream. Hope that helps.
6298176 tn?1380134459 It has a very long half life, though I can't give you specifics. The dose and how long you were on it does factor in. Your doctor should be able to help you with your questions on this.
Avatar f tn d ask my doc of course, and I know metoprolol has a short half life so maybe I just need to take the two doses a bit closer together. The pharmacist said 8-12 hours apart should be ok, but I am still getting some fast pulse in evening before my night dose. So would it help to start taking one 25mg tablet three times a day instead of just twice? Just to make sure it's in my system longer?
612551 tn?1450022175 Sorry, I made the calculation in an Excel document, the copy+paste function to the forum failed a bit. It's supposed to be 8 - 1,25 - 1,1, meaning 8AM - 1,25 mg intake (because 25 mg is released evenly through 20 hours) 1,1 mg is the effective concentration at that given time. It's lower due to the half-life and I've extrapolated the half life to count each hour. At approx. 20 hours you reach "steady state".
Avatar f tn If you take more than one in a 24 hour period, the effect of the drug is additive due to its long half life. Please be careful!
15256956 tn?1439425231 I was taking it twice a day to get the full effect for 24 hours (Metoprolol takes about an hour to get in your system and has a half-life of 6-7 hours), so yeah, while it sounded like a 300mg, it was really just 150mg per 24 hours. At the time, the physician (an FNP) didn't think to put me on the ER which would've been one dose daily.
443862 tn?1237999439 And I am questioning the competence of the PA who told me to take the last 6 halves of metoprolol 25mg every other day and then quit taking them period. I took half of a 25mg daily for 10 days prior and 25mg daily for about a month and a half before that. And I was on 50mg for I think maybe 5 or 6 months before being cut down to the 25mg. At first, the metoprolol seemed fantastic. Little did I know then that I would be taking a med that also would fix my bp..
Avatar n tn The half life of metoprolo is 3-4 hours. Meaning the drug reamaining in your system is reduced by 1/2 every 3-4 hours. The duration of it's effects is 13-19 hours. Get out your calculator and do the math. You took a very small dose for a very short time, so you should be close to having none left in your body. If you are still "feeling" effects after your "withdrawal," call your doctor and let them know. Not everybody metabolizes at the same rate.
Avatar f tn My interest in Atenolol was more than the half-life of the medication. As you may have read my experience so far confirms the Atenolol is longer lasting in my body... only one sample, others may get different results.
1933354 tn?1323362834 Keep in mind that when you switched from Toprolol ER (Metoprolol Succinate) to Lopressor (Metoprolol Tartrate), you lost the timed released advantage. If you were taking 25mg. pills of each medication, you are loosing a great deal of the latter drug's effectiveness as the day wears on. The half life of Metoprolol Tartrate is only 3-7 hours. So you must take it at least twice a day for it to be effective the entire 24 hour period. Also 25mg., once a day is a a very small dose.
Avatar n tn With some idea of the plasma half life of Metoprolol, and the dose strength, there is technically a small amount remaining. So to answer your question directly, yes, there is a cumulative buildup with each dose. But at that strength, it would take "forever" to build up. For some, the initial dose takes some getting use to. I've been on 75mg. for years, and feel no side effects of whatsoever.
Avatar m tn Propranolol has a reportedly better shortening effect on Long Q than Metoprolol. Are you taking Metoprolol Tartrate? Metoprolol has a very short half life; typically 5 hours or so. In that time, half of it is metabolized. Physicians usually prescribe Metoprolol to be taken twice a day beca use of his. MetoprololSuccinate is the time release version, and that is taken once a day. In addition 25mg. is an exceedingly small dose.
Avatar f tn Metoprolol 25 mg. Does it make a difference in what I'm taking, wether I can cut in half or not? The PA knows what I am taking and he told me just to cut it.
Avatar f tn i take the metoprolol tartrate 25mg one pill a day but i take 1/2 when i wake up and 1/2 at bed time... like every twelve hours basically and it has helped me with my sinus tachy.
Avatar f tn m on 75mg and have been as high as 200mg. If you look at the plasma half life of Metoprolol, at the end of the day, there is very little remaining in you blood. Are you taking it more than once a day? With Metoprolol Tartrate (the standard release kind) taking it only once a day creates these peaks and valleys as opposed to a more level dose.
Avatar m tn The nurse finally told me to break the pill in half and take half in the morning and half at night. That worked a little better. I ended up eventually on Atenolol which I have taken for 6 years. I take it in divided doses, as my bp or hr goes up or down. If my hr and bp are too low, I delay a dose. But I never just skip it. So I might take between 1-1/2 tablets over the day, sometimes 2 pills. I don't think you're supposed to just stop it.
Avatar f tn In fact, it has has groove where they give you a guide where to cut it, I just looked at my Metoprolol pills. If your doctor suggests you split the dosage in half and take one segment in the AM and the other in the PM I'd procede with great confidence.
Avatar m tn Metoprolol has the same bradycardia effect as Atenolol, so that has to be watched. Metoprolol has a serum half life of around 5 hours, the Succinate version helps to even the rate of absorption out. Admittedly, my dosage is somewhat of a roller coaster curve, but it seems to work well for me. Since my ablation procedure, I continue to take it for mild hypertension. It is very effective for that for me, so I was just kept on it.
Avatar n tn Hi Brooke, I have a call into the cardiologist. I have been plagued with palpitations most of my life. I am very healthy, exercise all the time and weight is fine. I have just had a bout over the past two weeks with hundreds of skipped/fluttering beats. I've eliminated morning caffine and have wine occasionally. I did take my BP and it is 146/83. The added does of beta blocker isn't working. They will probably need to adjust meds.....thanks for your support.
471161 tn?1317190950 Not the answer/help you're looking for, but I add my data point saying I've taken Toprol and Metoprolol in medium to high dose and have never had a chocking sensation. I do not know anything about Digoxin. If the chocking has not stopped with your discontinuation of Metoprolol I'd say it has/had nothing to do with the chocking.
Avatar n tn Hi - I have a question for all of you metoprolol users...is it possible to gain weight on 12.5 mgs per day? :( I'm a very active 53 yo woman (cardio 60 min daily, weight training 4x a week, martial arts 3 x). How is it possible that I'm struggling to keep from gaining weight? I'm currently looking at my calorie intake and also the macro allocation, but one would think with all of the cardio, sparring and weigh training keeping the weight off would be easy!
Avatar m tn Metoprolol Tartrate only has a half life of 3-7 hours. So basically, after 3-7 hours you have just 12mg in your blood, then after 6-14 hours 5-6mg which will then slow down in effect. I would ask your DOC if you can split the dosage to twice a day, or change to another type of medication. I had the same issue as you for years, trying to balance my meds. Finally, we now have the medication to exactly the right amounts. Each morning I now take 2.
Avatar m tn If it adversely affects you, stopping it will quickly eliminate it from your body. Metoprolol has a short half life of around 5 hours so it is metaboloized rather quickly, and its effect on you will quickly disappear.
Avatar m tn Metoprolol has a relatively short half life of 3 to 7 hours. In other words, when you take it, its medicinal benefit begins to lessen rather quickly. By taking it only once a day, you get a spike followed by a rapid lessening of its effect. People taking Metoprolol Tartrate usually take if twice a day to maintain a relatively stable level of the drug in their system. Another thing I wanted to point out is your dosage is extremely low. Body mass could play a factor on your dose.