Metoprolol half life

Common Questions and Answers about Metoprolol half life

toprol

If you take more than one in a 24 hour period, the effect of the drug is additive due to its long half life. Please be careful!
pills of each medication, you are loosing a great deal of the latter drug's effectiveness as the day wears on. The half life of Metoprolol Tartrate is only 3-7 hours. So you must take it at least twice a day for it to be effective the entire 24 hour period. Also 25mg., once a day is a a very small dose. I'm currently on 75mg as a maintenance doseage, and have been as high as 200mg. Just something to keep in mind.
Just to show I under stand at 12 hours the 12 hour half life is at half strength while an 8 hour half life is close to 3/8th strength at 12 hours. - off the "top of the head"... sounds about right. How do we beat this???? I find the fact that I occasionally forget to take my medications sort of resets my residual levels to near zero...
may hit you harder than someone,with more body mass. Also remember that Metoprolol tartrate has a half life of about 6 hours, meaning every 6 hours or so, your body metabolizes the dose to 50% of the original amount. So 25 halves to 12, then halves to 6, then to 3mg after 18 hours. You mention ablation in your profile. It could be a good way to get rid of it forever. A lot of folks here along with myself have hadn't done. Penn has sooe great docs.
Yes... You did tell me that. But i chose to take my drs orders instead - mostly bc as someone who constantly monitors my Bp and hr, I don't find it necessary to take twice a day. My heart rate stats around 70 and my Bp stays around 100/70 all day, I find no need to introduce even more of a drug into my body when I've been on the metrication for quite some time with normal readings when only taking it once every 24 hr....
Thanks Tom, I have read many of your post and was so inspired by your attitude and how you conquered your problems, I just pray mine will be as successful as your . Ive been on mine since May 22nd and have tried to come down to 50mg twice a day but my tacky doesn't like it, and I have made about 6 trips to the ER, hopeful he will find the extra passage and fix that too.
Metoprolol has an average half life of around 5 hours. So it's metabolized fairly quickly. If one goes in for an electrophysiology study, they will be told to discontinue Metoprolol (just) 3 days before the procedure as it's quickly removed from the body. So in your case, within 12 hours your original dose of 25mg has been greatly, but not completely metabolized when you take another 25mg. Slowly, you build up a therapeutic level.
Metoprolol has a rather short half life of approximately 6 hours, so in 24 hours, 50mg is nearly completely metabolized. This type should be taken twice a day. If you took the Tartrate version once a day, then the hills a valleys are smoothed out, so you have a reasonably even dosage in you system throughout the day. I can't offer you any legal advice, except "S" happens.
They all make me tired, some of them are worse and the Bisoprolol and Metoprolol are the worse for me in term of side-effects. The half-life of the Metoprolol is between 3 to 7 hours... some people are fast metabolizer and the effect will not last 7 hours and the drug will tend to not accumulate that much in the body and blood... I'm a fast metabolizer and with the Metoprolol it's even faster. I wake up around 7 AM and take 12.
I took 2 different versions of metoprolol, Toprol (metoprolol tartrate) and Toprol XL (metoprolol succinate). The second one is the extended release version. Toprol made my symtoms worse but Toprol XL worked fairly well in controlling my conditions, PVC's and PSVT. I was taking 50 mg a day in both cases. The only thing that affected me was a slight feeling of dizziness at times and some mental fatigue.
My interest in Atenolol was more than the half-life of the medication. As you may have read my experience so far confirms the Atenolol is longer lasting in my body... only one sample, others may get different results.
Here's the question- I am wondering if these PVC's and PAC's that I have been experiencing in the past 2 months have to do with suddenly stopping the metoprolol that I was on for my high blood pressure. I don't recall ever getting them before and now they occurring constantly..I was taking metoprolol 25 mg twice a day and then my dr discontinued it because I found out that I was pregnant. Now I am taking something else for the blood pressure that is safe to take in pregnancy.
I'd ask my doc of course, and I know metoprolol has a short half life so maybe I just need to take the two doses a bit closer together. The pharmacist said 8-12 hours apart should be ok, but I am still getting some fast pulse in evening before my night dose. So would it help to start taking one 25mg tablet three times a day instead of just twice? Just to make sure it's in my system longer?
Do you take any type of Beta Blocker for your palps? Metoprolol (Toprol) made my hair fall out BIG TIME. The hair loss is starting to slow now, 2 months after discontinuing the beta blocker....
By the way, you can compare similar weights of Metoprolol Tartrate and the time release version called Metoprolol Succicate if you consider the longer half life of the latter version.
Metoprolol has a relatively short half life of 3 to 7 hours. In other words, when you take it, its medicinal benefit begins to lessen rather quickly. By taking it only once a day, you get a spike followed by a rapid lessening of its effect. People taking Metoprolol Tartrate usually take if twice a day to maintain a relatively stable level of the drug in their system. Another thing I wanted to point out is your dosage is extremely low. Body mass could play a factor on your dose.
Not the answer/help you're looking for, but I add my data point saying I've taken Toprol and Metoprolol in medium to high dose and have never had a chocking sensation. I do not know anything about Digoxin. If the chocking has not stopped with your discontinuation of Metoprolol I'd say it has/had nothing to do with the chocking.
Metoprolol 25 mg. Does it make a difference in what I'm taking, wether I can cut in half or not? The PA knows what I am taking and he told me just to cut it.
The half life of metoprolo is 3-4 hours. Meaning the drug reamaining in your system is reduced by 1/2 every 3-4 hours. The duration of it's effects is 13-19 hours. Get out your calculator and do the math. You took a very small dose for a very short time, so you should be close to having none left in your body. If you are still "feeling" effects after your "withdrawal," call your doctor and let them know. Not everybody metabolizes at the same rate.
It's interesting to note that Metoprolol Tartrate has a fairly rapid half life. In approx., 5 hours after taking it, only 50% of the drug remains in your system. This is the reason you must take it twice a day to maintain a reasonable therapeutic level in your blood.
Metoprolol has a serum half life of around 5 hours, the Succinate version helps to even the rate of absorption out. Admittedly, my dosage is somewhat of a roller coaster curve, but it seems to work well for me. Since my ablation procedure, I continue to take it for mild hypertension. It is very effective for that for me, so I was just kept on it.
I always try to look at the glass as being half full and not half empty. Whenever faced with something bad, I try to find the good. Believe me, it took me a long time to get here. I was always planning the next pity party for myself. But one day, I just got up and decided to roll with the punches ,whatever they may be. For now, make sure that you drink plenty of water, get a good night sleep and see what tomorrow holds. I'll say a prayer for you.
I did a mistake for my actual Metoprolol tartrate dose. I take 25 mg at breakfast. I take 12.5 mg after lunch time. I take 25 mg after dinner and 12.5 mg before going to bed. Like I was saying, I don't find it effective for more than 4 hours, I must be a fast metabolizer but I feel like the half-life is much more like the Propranolol than the "apparently" 12 hours like most of the Cardio Doc suggest.
It's instantaneous. Metoprolol Tartrate has a relatively short half-life. That's why you have to take it twice a day. I was told by my EP to stop it immedately, and that it wasn't necessary to gradually reduce it. this was prior to my cardiac ablation for SVT. But, do as instructed by you physician. I take 75mg a day, and am totally accustomed to it. Your body balances itself within a few weeks. I had dosages up to 200mg per day. That, I had a hard time with.
I am about to begin withdrawal of 50mg Metoprolol after 5 years addictions to it for blood pressure only. No heart issues. It has been used with 5mg Norvase - Calcium Channel Blocker. PCP's instructions are: 1. Stop the Norvase for 20 days to see if BP spikes. If not then proceed to: 2. Reduce from 50mg of Metoprolol twice a day to 25mg twice a day for one week. 3. Then, 1/2 a 25mg tab twice a day for one week. There was the expectation that there could or would be BP spikes. WHY?!
I'm a 46 year old male with a long (15-20 year) history of migraines, they have been gradually getting worse over time. I have been unable to work for the last year and a half, and have been bedridden for the last year due to a severe headache. The headache has not gone away at all during that time. Five years ago I had a bad stretch that I was off for about a year but not necessarily bedridden the entire time. The rest of the time I experienced what may be considered regular bad migraines.
You may have seen some of your darkest days. Perhaps you reached the very depths of despair while battling opiate addiction and or dependency. But there is hope that you can recover fully. Opiate abuse and addiction can wreck lives. It can take hold of you both physically and mentally with a grip so powerful you may do things you never thought you would out of desperation. It can cause you to steal, lie, cheat and dishonor yourself and those you love.
Metoprolol has a half life of around 3-4 hours where Bystolic is around 10-12 hours. In other words, put 10mg into your body now, then in 3-4 hours, there will be 5mg in your body for metoprolol. Bystolic side effects http://www.drugs.com/sfx/bystolic-side-effects.html Metoprolol SE http://www.drugs.com/sfx/metoprolol-side-effects.
Took my metoprolol half tablet at 10 pm last night as usual. It never did feel like it did anything. Maybe it was a bogus pill. I had tachycardia, palpitations, irregular hearbeat on and off all night. Kept waking up suddenly out of breath. By 4:30 am I was so exhausted I could barely lift my head. I felt like all the life was draining out of me. Ken took my pulse and said it was very fast and thready. Told me to take another dose of metoprolol. I did. One hour later I felt normal again.
Best to check with your doctor... I don't know your specific medicine, but in the case of a beta blocker I have chosen to take the the regular release at 1/2 does level rather than the slow release full dose once a day. I did this for two reasons: regular release available in a very inexpensive generic version (Atenelol or Metoprolol), and two I have more confidence in getting medicated 24/7 as one each 12 hours I give it a boost.
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