Metoprolol grapefruit interaction

Common Questions and Answers about Metoprolol grapefruit interaction

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Avatar n tn can I drink the juice of 1 grapefruit a day, if I am taking metoprolol and fosinopril for blood pressure? My blood pressure is completely controled.
Avatar n tn A list of medications that have been shown, in clinical studies, to have an interaction with grapefruit juice can be found in the table below. All of the medications, except for theophylline and itraconazole, are known to be substrates of CYP3A. When given with grapefruit juice in pharmacokinetic studies their availability increases. In most cases, the clinical consequence of the pharmacokinetic interaction has not been evaluated.
612551 tn?1450022175 Thanks, that may be the reason my shift to Atenolol from Metoprolol seemed to require a lower dose. I haven't eaten grapefruit for a few days and it appears my side-effects from Atenolol have subsided. I will continue to take a slightly lower dose, now at 25 mg morning 12.5 mg night, then go back to the 25 mg morning and night. As discussed in another post by me on the BB subject I was experiencing very low HR when in bed, and some serious dizziness.
Avatar m tn Citrus juices, specially grapefruit, CRANBERRY and orange juice, interact with heart and blood pressure medications. By inhibiting the same enzyme that metabolizes the Metroprolol, the juice raises the levels of the drug in your blood and it can cause an overdose. Your doctor should have known that. Page 6 talks about the interaction of medications with cranberry juice...... http://www.fda.gov/cder/drug/drugInteractions/pubs/2004_Huang_Lesko_drug-food_interactions.
Avatar f tn thanks Research about the interaction of grapefruit juice with drugs suggests that compounds in grapefruit juice, called furanocoumarins (for example, bergamottin), may be responsible for the effects of grapefruit juice. Researchers believe that furanocoumarins block the enzymes in the intestines that normally break down many drugs. One glass of grapefruit juice could elicit the maximum blocking effect, and the effect may persist for longer than 24 hours.
Avatar m tn I like to drink grapefruit juice but hear that it can interfere with some prescription medications. Is that true? Answers from Katherine Zeratsky, R.D., L.D. Yes. Grapefruit and certain other citrus fruits and products can interfere with several kinds of prescription medications. Don't take these interactions lightly. Some can cause potentially dangerous health problems.
12182312 tn?1427683956 SSRIs like paroxetine are a type of antidepressant that works by increasing the amount of serotonin in the brain, while metoprolol is a beta blocker which works on the heart. What type of metoprolol are you taking. Metoprolol Tartrate or Metoprolol Succinate?
Avatar n tn Has anyone had problems with Zoloft side effects as a result of eating grapefruits? I started taking zoloft (100 mg daily) just two months ago and have not gotten over what I thought were the initial symptoms--dizziness, drowsiness, itchy skin. I was so tired all day long that I found I had to drink up to 7 cups of coffee a day to stay awake. While reading an old magazine, one title jumped out at me, "Grapefruit Concern".
Avatar f tn Are there any risks/side-effects associated with taking Metoprolol 23.75mgs prescribed for non-sustained VT and Phentermine 37.5mgs prescribed for obesity? Thanks.
142526 tn?1397090672 While you are taking this medicine, you should avoid eating grapefruit or drinking grapefruit juice. You may choose an alternative citrus beverage (such as orange juice). In the event that you are instructed by a healthcare professional (e.g., doctor, pharmacist, or dietitian) to eat grapefruit or drink grapefruit juice you should discuss with your doctor the effects of grapefruit on the blood levels of this medicine.
Avatar m tn This, initially the drug does not completely metabolize and has an extended half-life. This why it is dangerous to take grapefruit juice with certain medications. Follow me on this. You take a substance that reduces the production of these enzymes (say grapefruit juice) and for the first four hours the drug does not fully metabolize. After six hours the grapefruit juice wears off, the liver again starts producing these enzymes, and you take a second dose of the medication.
20748650 tn?1521032211 I did see some information regarding an interaction between metoprolol and this product, but it pointed to an increase in metoprolol bioavailability, which theoretically shouldn't adversely impact the PVC burden? Anyone have any input or knowledge.. Even similar personal experiences with this?
Avatar m tn No interaction between both drugs. Note that some aliments like citrus, grapefruit extract can increase the potency of some drugs which is considered an interaction.
Avatar f tn i need to know that, what is the interaction between juices of Grapefruit and Hepatitis C? is there any reactions of Grapefruit juice being taken by Hepatitis C patient?
Avatar m tn The interaction caused by grapefruit compounds lasts for up to 24 hours and its effect is the greatest when the juice is ingested with the drug or up to 4 hours before the drug. [10] It is demonstrated for the first time that lemon juice significantly inhibits by 60 ± 3% the CYP3A4-mediated oxidation http://cat.inist.fr/?
Avatar f tn There is an interaction between grapefruit and almost every medication known to man. When it come a to mental health medications grapefruit is a very serious danger. I am glad you are ok and have patience because things will go back to as they were. Grapefruit and st. Johns wort are to things to completelt avoid while taking zoloft and/ or other mood balancing/ altering medicines.
Avatar m tn //www.drugs.com/prograf.
Avatar n tn Naringenin interferes with drugs, so you should not take it while on treatment. If you google Naringenin drug interaction or grapefruit drug interaction, you will find a lot of info on the subject.
1175033 tn?1492201228 I started taking Valium recently and noticed that the bottle warned not to consume grapefruit of the juice at all while taking this medication. This was a issue for me because I drink hansen's natural cane sugar soda with real grapefruit extract and I had to give that up, but I really didn't want to so I read up on what it will do. One article I came across said it would increase the potency of certain meds by 400% http://www.mayoclinic.
Avatar n tn I was diagnosed with PVC's 15 years ago and was put on Metoprolol 25 mg. I've now been diagnosed with depression and was prescribed Prozac 10 mg which I'm afraid to take now because of the drug interactions I've seen on the internet with these two drugs. Can I run into problems by combining these two drugs.
Avatar n tn * Anthelmintics (Used for treating certain parasitic infections, includes praziquantel albendazole and mebendazole) * carbamazepine (Tegretol) Grapefruit or grapefruit juice slows the breakdown of this drug, increasing the level of it in blood * Loperamide (Imodium), the anti-diarrhea drug * colchicine (Colcrys) The CYP3A4 isoform of cytochrome P450 is located in both the liver and the enterocytes. Many oral drugs undergo first-pass (presystemic) metabolism by the enzyme.
Avatar m tn I currently take Amiodarone 200mg a day, Metoprolol 100mg a day, Prilosec OTC 40mg a day. I have occasional Atrial Fibrillation. I was put on the Metoprolol in 2004 (my dosage is much lower now) and the Amiodarone in July 2008. I suffer greatly from panic attacks and extreme anxiety. My doctor prescribed Zoloft for me at 25mg a day for two weeks, then 50mg a day thereafter. He knows all the meds I currently take, of course.
Avatar f tn I'm currently on Suboxone 8mg daily, my doctor just gave me metoprolol succ. 25mg. I've been tachycardic ranging from 110-150 so she wants to slow my heart rate and pressure but I'm terrified to take the medication because of interaction and slowing my heart too much. What do I do?
Avatar m tn Thanks, Rocker, for posting all that. I was curious about the grapefruit-drug interaction, but had not done the research. I was told to avoid grapefruit during tx. Is that a standard of tx, to avoid grapefruit, I mean, is everyone told that by their caregivers? Just curious.
976606 tn?1263667593 I'm not sure what the official medical answer is regarding grapefruit juice and Synthroid, but I have never noticed a difference when I drink pink grapefruit juice vs. any other juice. I know grapefruit juice is a no-no with certain meds (my Mom can't drink it because of one of her post-heart attack medications), but I have never seen any warnings regarding synthroid.