Methadone ld50

Common Questions and Answers about Methadone ld50

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Avatar f tn The LD50 for Water is 90g/kg. But when does nerve damage occur, if you trink too much water at once? When does it become toxic? Empirical data is also appreciated...
Avatar f tn What is Methadone?: Methadone is an opiate that was first introduced after World War II as an alternative to morphine. Methadone was originally thought to be less addictive because of its extremely long half life. Today, methadone is used as an analgesic for pain management and more popularly as replacement therapy for heroin and other opiate addictions. Methadone is a cheap alternative to other opiate based medications which outweighs it potency when prescribing.
Avatar f tn However, Italian researchers have found that the LD50 (the lethal dose at which half of the animals die) of glucosamine sulfate is 8000 mg/kg. In humans this would be equivalent to ingesting over 500,000 mg at one time or 1,000 pills each containing 500 mg. I hope this is useful... I got the idea from the site that max safe dose is 1500mg, and your dog had twice that much. You may want to see the vet anyway, even tho it says in the previous paragraph that a lethal dose is 8000mg.
Avatar n tn my dad is 83 yrs old, has emphysema, copd everything...hes on ox, however he still struggles to breathe, won't allow anyone to go into the doctors office with him ! I know he is in stage 4, how long does that last? its been like this for a couple of years, he has difficulty even walking across the room and says that its a task to urinate. is there anything we can do as a family to make him more comfortable?
Avatar n tn opiates will make your spew, but i dont think the codeine even in high doses makes you sick, iv had 240mg of codeine before and it just makes you feel real high for a couple of hours, ulcers would be causing him pain,so im not so sure if its ulcers.HOw many is he taking at one time?
Avatar m tn This only becomes an issue if you are taking mega-doses of those vitamins and lose a lot of weight - suddenly, your body could be overdosed - there is an LD50 listing for vitamin A of 2000 mg/kg - LD = lethal dose, LD50 = 50% of the population will die at that dose, 2000 milligrams per kilogram of body weight. Anyone who tells you that herbs will not hurt you is just wrong.
Avatar m tn I know that this forum isn't adequate for my question but I am new to this site please forgive me for this. I am 17 years old, and 80 kg. My issue is I have just taken accidentally 10 grams of paracetamol aka acetaminophen I've just read that the ld50 is >250mg/kg so by this it means that the dose for me to die is 20 grams. Will I be safe for the next 24 hours because I can't seek any medical help for this time, what should I do? I am really scared.
1264367 tn?1408104163 I have gastroparesis, and GERD, and am on methadone maintenance. I noticed I started having problems as soon as I started the Methadone Clinic, 3 yrs ago. I recently had an endoscopy and waiting on the biopsy results. I'm so sick of not being able to eat anything. I'm living off of oatmeal and can't over eat. But it's not over eating because I've been starving. I can only eat a small bowl of oatmeal before I take my methadone and then another small one for lunch.
Avatar f tn Some meds need to be separated by a short period of time. I guess these are more specifically SSRI's and MAOI's. I didn't see a major problem with the meds being taken consecutively. This should always be at the discretion of ones doctor though. I guess I neglected to emphasize the importance of only ever making medication changes after consultation with the treating physician. There are a number of factors to consider when changing meds. Withdrawal is only one.
Avatar f tn i am on methadone maintenance for opiate addiction, if methadone is also an opiate blocker what prescription meds will give me relief from my pain? i mean, do i take higher doses of opiate to get relief from my pain or is there a certain pain med i need to take while on methadone to get relief from my pain? please HELP!!!!
Avatar f tn i agree with the others i would not take methadone to come off of tramdol at all because the w/d from methadone is 100x worse then tramdol ever could be. I am on methadone and its helped me but also when I come off it will be hard. You can read all kinds post on here about m'done detox....
Avatar f tn Hi I am new to Medhelp so if I double posted I am sorry. Anyway I am preg and was addicted to hydrocodone 10 mg 3X a day. I wanted to just stop cold turkey but was unable to cause of the WD and being preg. I went to a Dr w/my OB's advice to get on Suboxone,but he wouldn't cause he said Methadone is what is used while preg as it is safe? He started me on 10 mg 3X day which is WAY to strong so I am now trying 5mg 2X a day.
Avatar f tn Most physicians have little to no experience with (or much knowledge of) methadone and how it works and especially methadone and pregnancy. A doctor must hold special licensing to prescribe methadone for opiate addiction, and have the appropriate opiate-substitution training to do so. Therefore, you may not always get the current or correct advice from a general physician or OB-GYN. Your methadone clinic can't steer you to an OB-GYN with the correct addiction training.
Avatar m tn I am no doctor but it is my opinion that you will go thru withdraw from the methadone, which is much worse than hydro. Methadone has a very long shelf life. Please be careful mixing the done with anything. A whole bunch of people that I know have died doing just what you are doing. Methadone stays in your system a long dang time. Be careful because when you play with fire you will get burned. If I were you, I would stay far away from the methadone. Just my opinion.
14496752 tn?1434842374 ve used my share of methadone. The only drug that can give methadone a run for its money regarding withdrawal horror stories is Subutex/Suboxone.
Avatar n tn My opinion is throw the methadone away.One milligram of methadone is equal to 3 milligrams of morphine,so ten milligrams of methadone isn't such a small dose at all.I know it's rough but YOU CAN DO THIS and you don't need that methadone,it's not worth the risk.Sadinmichigan has a journal entry pertaining to methadone written by a doctor who treats patients comming off of it,you should give it a look.Best of luck to you....
Avatar f tn As with heroin and all other opiates, methadone tolerance and methadone dependence usually develop with repeated doses. Tolerance to Methadone administered in a pain-control program usually occurs during the first few weeks of use; whereas respiratory depression, sedation, and nausea can be seen immediately.
434196 tn?1206385870 I have a friend who is prescribed methadone and 5mg oxycodone. And I always thought methadone was a opioid blocker. So wouldn't that bock the oxycodone??
Avatar f tn That is an interesting question, but I suspect it is not the one you really want to ask. Methadone per se, does not damage the heart, however long term use of methadone does slightly increase the mortality from heart disease. The etiology (and reasoning) is as follows. (1) Methadone affects respirations. A person on methadone will have a slighty-less that optimal resting breathing rate.
Avatar n tn HI you can get methadose from a doctor and pick it up at a pharmacy it is methadone in pill form methadone is usually liquid and is dispensed at clinics you have to go every day to get it most doctors cannot prescribe methadone hence why so many go to the clinics this is nasty stuff I was on it 6 1/2 yrs I would run the other way if someone ever offered to me again it is not a way to get around withdrawals methadone withdrawals are some of the worst you can experence your best off to detox wha
Avatar f tn My doctor gave me methadone to wean myself off of the 8-9 norco's (vicodin) I was taking per day for chronic neck pain since a car accident in 2007. The first day on a low dosage of methadone seemed to work for me and I needed less of the norco's. However, the second day on the methadone gave me a horrible reaction -- I couldn't even get out of bed. I had a constant headache.
Avatar f tn I have been going to a methadone clinic for 7 years, but I have started a new job that their hours will not agree with the clinic. Please help me with finding a Dr. that will write methadone in their office, please, I need someones help!!
Avatar f tn Please consult a doctor. Methadone is not something you want to try and take on your own. You are correct in being scared of it. I have heard many horror stories about people taking it without being under the supervision of a medical proffesional.
Avatar n tn I’ve been prescribed 10mg methadone x2 daily and 2weeks ago my dr changed it to 10mg OxyContin x2 daily. I now have double vision and am listless and cold. I have several methadone left from my old prescription. Would I be able to change and take the methadone instead of the OxyContin until I can talk to my dr on Monday. I was told the change was due to something from my blood work showing up wrong?
Avatar f tn they are speaking of using benzos like xanax after you have stopped the methadone and are in WDs....I have never taken methadone but my son worked at a clinic and if the person tested positive for benzos they could not have their dose and it was against the rules...You should talk to your doctor about any medications u decide to use...especially if you are still taking methadone....it is good that you are interested in quitting..lots of support here..