I had been on the oxycodone for five and a half years, and within two days of taking 10mg
methadone every four hours and using the oxycodone 15mg now every four hours
for breakthrough pain, the methadone is working SO well that I don't even have to take the oxycodone every four hours, and when I do, half a tablet (as opposed to two tablets, which is the dose) is enough to control the breakthrough pain. I never would have believed it, but it is AMAZING!