hey james, i as on and off methadone for 15 years, in 2004 i kicked for the final time, i was getting 2 weeks take home, 200mgs 14 bottles,i was averaging 300 to 400mgs a day, my detoxed was a bit complicated the last time, in the past i could go cold turkey off methadone with about 3 weeks discomfort, and i always got back on drugs because i refused 12 step meetings, now in 2004, i had serious liver problems and my bodied had become atrophied, i was rushed to icu i believe it was my second week