I had serious diarrhea but eventually your body adjusts and MOST women start to tolerate it after a while. I've had much more success
with an extended release brand name version called Glumetza. First of all, when I was on the regular stuff, I was supposed to take it three times a day, and I NEVER remembered. This is extended release, so I take it at night - four pills. It is very expensive though. I have insurance and I still pay almost $60/mo for it!