Other 5-ASA agents, such as olsalazine, mesalamine
, and balsalazide, have a different carrier, fewer side effects
, and may be used by people who cannot take sulfasalazine. 5-ASAs are given orally, through an enema, or in a suppository, depending on the location of the inflammation in the colon. Most people with mild or moderate ulcerative colitis are treated with this group of drugs first. This class of drugs is also used in cases of relapse.