changes in
menstrual cycle (which can include irregular periods, no periods, and spotting); fatigue, weight gain, headaches, and sometimes dizziness. Another fact to be aware of is that once you stop Depo injections, it may take several months for your menstrual cycle to become 'normal' again. Although you can become pregnant after stopping Depo, it can take several months to a year before you're able to conceive.