I think your best bet is to consult an OB. Unfortunately, from my experience and others, doctors tend to be very pessimistic about conception
in your 40s. Should you conceive, see an OB right away.
I think if a woman wants to try, she should. Like any woman trying to conceive, a back-up plan for life after ttc and a rationalized end date should help in coping with the fertility roller coaster.