I've been on Rebif 22mcg (not 44) for
almost 3 years -- no relapses.
The "flu-like" symptoms are really mild, & I rarely get them. Mostly a morning-after headache occasionally. Once or twice a major episode with chills, joint pain, etc for
a few hours.
I also take Advil an hour or so befor
e, and I warm the injection site; make sure the syringe is at body temp.
I DO get big red spots that last for
weeks, but no pain, itching, etc.