I was having all the symptoms of fibro. including the
muscle pain and stiffness all over,
muscle spasms, sleep problems, irritable bowel, anxiety, depression, fatigue, etc. (the lastest is GERD). Unfortunately when I started the progesterone cream, my pain, muscle spasms, anxiety and sleep problems got worse. I was advised that this can happen initially as some woman convert progesterone into testosterone and estrogen first, but this should improve.