lovenox weight based dosing

I had an ablation last week and am doing well, but am very beat up (low energy, black and blue, sore throat from TEE and polka dot bruises from Lovenox). My question is how long a time period is it usual to be on Lovenox? My doctor has said a full month. From my research, other than pregnant women, for all other conditions it says 2 weeks or less. I can't take coumadin due to a severe reaction to it.

I am in a trial that will be comparing ribavirin dosing, weight based compared to concentration controlled based on AUC 0-12 after first dose. http://clinicaltrials.gov/ct2/show/NCT01097395?

If the standard weigh-based doses are 13-15 mg Riba per Kg and Peg at 1.5 mcg of Peg per Kg, you are only a hair less on both. I think it's part of the risk/reward aspect with trials. On one hand you are getting free meds and the 'new stuff' on the block and a lot of attention. On the other hand, there is less of a possibility for treatment 'stylizing' and things like rescue drugs might not be available.

I just got back from my high-risk OB appt and they have switched me to Heparin (Low-Molecular Weight, I believe) because it IS reversible should I go into labor unexpectadly, whereas Lovenox is not. I can't remember the reversal med, but it exists so that should I require an emergency c-section, they would give me this shot and send me on my way. The gal that asked me the question wanted to know about risks of c-section while being anti-coagulated.

29 weeks pregnant, ultrasound today showed birth weight of 2 pounds and 2 onces. Have been atenolol 25mg daily since beginning of 2nd trimester. Plan to have c-section at 37 weeks due previous t incision of uterus and post op PE, also on Lovenox 40mg SQ daily. I am very concerned if I should stop taking atenolol.

Summary of Key Conclusions * Dosing according to glomerular filtration rate (GFR) may be preferable to weight-based ribavirin among ribavirin-treated HCV genotype 1/4 patients with poor renal function * Poor renal function (low GFR) associated with o Lower sustained virologic response (SVR) rates o More adverse events o Possibly due to nonoptimal ribavirin dosing * GFR varied according to sex, age, and genotype but not according to weight or body mass i

While statistically less anemia was observed in patients treated with TBV compared to RBV, the primary efficacy endpoint of these studies, a non-inferior SVR between the TBV and RBV, was not achieved. Detailed subgroup analyses of the data suggest fixed dosing as opposed to weight-based dosing, and the selection of an inadequate dose, are to blame.

We are 8w5d pregnant now. Our RE recommended Lovenox/Prednisone/Baby Aspirin. How do you know when it's safe to stop each med? Nurse said it's usually through 12 weeks. But I have seen other people say online they took Lovenox until 36 weeks. Since this protocol worked, I'm scared to stop any of them. Thanks.

i give birth 6 weeks ago i had blood clots in my lungs they gave me lovenox inj? the medicaid was covering it, but now after my pregnancy ended they stoped the medicaid and i cannot afford seeing the dr or the inj. i still got 5000mg heparin but i dont use because after my pregnancy ended they swithed me to lovenox i now take only asprin 325mg am i at risk what can do about it !!

The last time I had Lovenox was one year ago and I was at 2.6 when I started the Lovenox. At that time I quit taking coumadin until after the procedure. The day after the procedure, I started up on coumadin and continued to taking the Lovenox until I was therapeutic again (between 2-3 INR). You stated that you were worried about the AFib. I assume you were referring to AFib while you are off coumadin and on Lovenox. I wouldn't worry about that.

Hi. I am 4 weeks pregnant, and it was highly suggested (based on the results of bloodwork drawn right before I became pregnant) to take daily Lovenox injections, as I am at risk for bloodclots. This has been the most miserable part of being pregnant, as I am a little wimpy about giving the injections... I am just wondering if anyone else is on or has been on this regimen and and have any luck making it a little less painful and any trick of the trades with avoiding the bruising... THANKS!

First congratulations and good luck with treatment! I just read in a previous post of yours that your nurse advised pre-dosing while your doc suggested starting peg and riba the same day. If you still have time to reconsider, I'd say go with the Nurse, at least for me it's a more cutting edge approach and I see very little downside, only upside. Recently, our resident liver specialist, Dr. Dieterich, had some favorable comments regarding pre-dosing.

Long story short, my B-12, Ferritin and DHEA levels were low. My FREE T3 and T4 were normal, as was my previous TSH. However, based on my symptomology - especially my low blood pressure and low body temperature - he has started me on Armour (as well as supplements of B-12, Iron and DHEA). Starting dose was 15 mg for one week, and now I have been on 30 mg for one week.

They suggest that the larger question of whether true weight-based dosing of ribavirin is superior to the currently approved standard dosing schemes still awaits head-to-head studies to answer. "At the minimum," they conclude, "the traditional notion that ribavirin dosage should be fixed has now been sidelined by the idea that we should tailor ribavirin dosing to our patients.

(48kg) when treatment started your doctor did well by you to start you on 1000mg,which would actually have been quite high given the guidelines for weight based dosing. However it is most important to get the maximum amount of benefit from Ribavirin early on(especially in the first 12 weeks ) and secondly until UND. Because you were undetected at week 4 and still at week 12 given your weight and how much time has lapsed it would seem your dose is fine. Your are currently taking 800 (16.

I hope people keep in mind that adequate ribavirin is what's required, not as much as you can shove into your system and not keel over. The absorption / concentration factor is a very interesting one that I'd like to see and read more studies on.

94 mg per kilo, at 1000 mg per day you would be taking 15 mg per kilo which would be a good dose. The problem is that weight based dosing doesn't mean you are absorbing the riba. Hopefully someone with more experience with geno 3 and pegasys will help out here.

Do you know your current TSH level? While high TSH should not be the only criteria for diagnosis or dosing medications, it can be an indication that something is awry. Please feel free to post that, as well, if you know what it is.

Recently, data from the Individualized Dosing Efficacy vs Flat Dosing to Assess Optimal Pegylated Interferon Therapy (IDEAL) study has provided a within-trial comparison of these 2 peginterferon regimens when used together with weight-based ribavirin dosing and demonstrated that SVR rates and tolerability were equivalent (Capsule Summary).

What I did was stop the Coumadin 5 days before, and then 4 days before started Lovenox to bridge up until the surgery (Lovenox is a subcutaneous injection and is a Low Molecular Weight Heparin that will keep the blot thin enough to prevent clotting). The night of the day of the procedure I had, I restarted the Coumadin, and the following day after the surgery used Lovenox for 2 days giving the Coumadin time to begin building back up again.

75 kg = 1000 mg 48 weeks ≥ 75 kg = 1200 mg 48 weeks Genotypes 2, 3 1 80 mcg 800 mg 24 weeks It looked a lot nicer as a table on-line but would not cut and paste that way. Ribivirin dosages are weight-based. Do whatever your doctor says. If it is wildly different from the recs.

Of note, within the weight-based ribavirin group, SVR rates were consistent across all weight categories, whereas SVR significantly decreased with increasing weight in the fixed-dose group (Figure 5). Weight-based ribavirin dosing could be considered for those patients that may be more difficult to treat due to underlying host characteristics such as obesity or advanced fibrosis.

Lovenox weight based dosing

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