Lovenox dosing for obese patients
Common Questions and Answers about Lovenox dosing for obese patients
lovenox
I had an ablation last week and am doing well, but am very beat up (low energy, black and blue, sore throat from TEE and polka dot bruises from Lovenox). My question is how long a time period is it usual to be on Lovenox? My doctor has said a full month. From my research, other than pregnant women, for all other conditions it says 2 weeks or less. I can't take coumadin due to a severe reaction to it.
If you are on triple therapy for genotype 1 and undetectable then your doc is following AASLD protocol for anemia management
Anemia developed among recipients of both PIs. Hemoglobin decreases below 10 g/dL (grade 2 toxicity) occurred in 49% of patients who received a BOC regimen compared to 29% of those who received the SOC
regimen, whereas 9% had a hemoglobin decline of <8.5 g/dL (grade 3 toxicity).
Routine monitoring of calculated creatinine clearance and serum phosphorus should be performed in patients at risk for renal impairment.
Dosing interval adjustment of VIREAD and close monitoring of renal function are recommended in all patients with creatinine clearance <50 mL/min [See DOSAGE AND ADMINISTRATION].
I was on lovenox for a short period of time. I could not find a spot for the injection that didn't make me cry. I'm sorry you are going through this.hopefully they can switch you to the heparin by mouth instead. They told me that they normally keep ppl on the lovenox until wk 37 b.c it's longer acting and then the heparin after that b.c it's out of your system faster and is safer foe delivery bit maybe you can get switched earlier?
Good luck!
7 compared with those with genotype 1, cirrhotic patients had an OR of 0.15 compared with noncirrhotic patients, and obese patients had an OR of 0.23 compared with normal and overweight patients. Hepatic steatosis was not an independent risk factor for response to antiviral treatment. In conclusion, obesity, only when defined as a BMI greater than 30 kg/m(2), is an independent (of genotype and cirrhosis) negative predictor of response to hepatitis C treatment.
Retrieved from http://www.ncbi.
It should not be used by anyone who may want to get on a transplant list. As drug or alcohol abuse are conditions for not listing patients for liver transplantation.
From the Mayo Clinic
"Major categories of pain medications, including over-the-counter analgesics (OTCAs) such as acetaminophen and nonsteroidal anti-inflammatory drugs (NSAIDs), as well as cyclooxygenase 2 (COX-2) inhibitors, anticonvulsants, antidepressants, and opioids, are largely metabolized by the liver.
Patients treated with TBV had less than half the anemia compared to RBV treated patients. These results suggest weight-based dosing of TBV can significantly improve the tolerability of HCV treatment while maintaining efficacy. Specifically, the 25 mg/kg dose offered the optimal balance of efficacy and safety in this patient population.
Notably, fewer patients treated with TBV required dose reductions (13-28%) compared to 32% of patients treated with RBV.
When you go in for more tests, please make sure they test for Free T3 and Free T4 (not the same as Total T3 and T4), along with TSH they always want to test for. If the doctor resists, then you should insist on it and don't take no for an answer. Since there are reports that the best measure of tissue thyroid levels is the ratio of Free T3 to Reverse T3, I would also suggest that you test for Reverse T3, to establish a baseline.
Since my surgery is so close he put me on Lovenox for now. He also told me when he puts me on Comaden?? after the surgery I can't eat greens -they contain vitamin K.
So I then went to the anticoagulants unit where a pharmacist showed me how to administer this medicine and she told me that it would be ok to take tonight even though I already took a baby aspirin and to call her to see if I should continue taking my aspirin with the Lovenox ( not wantint to step on the Nuerolgist toes).
Lovenox and Plavix are both anticoagulants (antiplatelets). These reduce the chance of clot formation which can result in stroke. This is typical treatment when patients present to the ER with symptoms of chest pain. This is not likely to be causing you your current problem.
Your anxiety could most definitely be impacting your heart rate as well as your BP. You should try to relax and see if your symptoms resolve.
Routine monitoring of calculated creatinine clearance and serum phosphorus should be performed in patients at risk for renal impairment, including patients who have previously experienced renal events while receiving HEPSERA®.
Dosing interval adjustment of VIREAD and close monitoring of renal function are recommended in all patients with creatinine clearance below 50 mL/min [See Dosage and Administration (2.3)].
That depends on your doctors comfort levels in prescribing , a patients ability to tolerate side effects, other medical conditions, effectiveness of using opiates, but typically- most physicians will not prescribe over 90 to 100 MME mg dosing per day-(Morphine equivalent dosing per day)- and typically only for patients who have been on opiates for some time. MME dosing combines both long acting and immediate release types of opiates to reach 90-100mg MME daily.
There were no issues with toxicity, that data has been reported. He surmises the reason they are going for higher dosing in Aus is due to efficacy, however they just released that dosing has just begun so that info would be available yet.
My belief is they are just wanting to see the safety profile with higher doses in case they are required for greater knockdown.
The pivotal trials that supported approval of the HCV protease inhibitors telaprevir and boceprevir (Victrelis) -- the first direct-acting antiviral agents for hepatitis C treatment -- administered both drugs every 8 hours. But this dosing regimen is inconvenient for patients, which may result in missed doses and reduced effectiveness.
I also have the same issue. My IGM first came back borderline and then the 2nd 2 tests were just slightly positive. I don't have any history of miscarriages. I'm on 40mg Lovenox a day and have been spotting brown blood for past 2 weeks. I have heard Lovenox causes bleeding. I don't think I need to be on Lovenox. My Rhemetologist said some docs would think Lovenox is necessary while other docs would think I wouldn't need Lovenox.
I dont know anything about the lovenox but im sure your Dr knows whats best for you.
To tell you the truth Im not for sure why Im taking Lovenox...we have 2 children and had no problems getting pregnant,etc..For some reason when I turned 30 I had three mc back to back..we were going to a fertility specialist and finally was able to get pregnant again the doc put me on lovenox,baby aspirin, and progesterone..looks like everything is going fine with this pregnancy..Im 9.3 weeks due Feb 21st.
Setrobuvir also showed an excellent safety profile in the study through the 12 weeks of dosing, with reported adverse events being typical for patients treated with interferon and ribavirin alone, although conclusions regarding safety cannot be made until results in more patients over longer duration are known.
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