Losartan mechanism of action

Common Questions and Answers about Losartan mechanism of action

cozaar

Avatar m tn Hello, I African American male in my 40's that have been dealing with my blood pressure running 140/ 90 for a while my doctor put me on Losartan HCTZ 50- 12.5 and my pressure. After my 6 months check up my pressure was still the same so he increased my Losartan to 100-12.5 and a few weeks after I would get readings of 130 /80 sometimes and others I would get 129/78.
Avatar n tn Tests on their livers revealed that, before treatment with losartan, half of the patients had a high level of the biomarker NF-kB. After treatment, the level fell indicating that losartan is able to switch off NF-kB with the result that scars are no longer produced or maintained, but instead shrink.
Avatar m tn I am not physically restricted - I walk 1 mile or more day and do 10 minutes of other light exercises most days. My BP runs under 120/80 most of the time. I understand carvedilol helps prevent stiffening of the heart muscle and can help restore LV function to some degree. How specially, so it do this? What is the biochemical mechanism?
Avatar m tn I am taking Losartan, which is the generic of Cozaar. Like Benicar (which is not available in generic yet, I believe) it is an angiotensin II inhibitor. There are usually very few side effects associated with these drugs, but their action on the biochemistry of the body is complex, so anything is possible. I have Hashimoto's disease, which means I am HYPOthyroid. Before the Losartan, I was taking 90 mgs of Armour (which is T3 AND T4) daily.
Avatar m tn as a starting point for your research, realizing that losartan is probably the weakest ARB out there and that others are much stronger. I realize Marfan has been ruled out but the mechanism for action in these drugs appears to be the same for other connective tissue diseases. After reading up on the research, contact the clinic of Dr. Hal Dietz at Johns Hopkins for an evaluation or for a recommendation for a more knowledgeable pediatric cardiologist in your area.
Avatar f tn Losartan is not a beta blocker. Instead it is an ARB. By blocking the action of angiotensin, losartan relaxes muscle cells and dilates blood vessels, reducing blood pressure. It can cause nasal congestion and persistent cough, Since you have both the cough and leg swelling, you should ask to try another bp medication. There are other types.
Avatar m tn Unfortunately the HCV was not eliminated and when I ran across an article that indicated that losartan(Cozaar) a blood pressure medicine may reduce or eliminate fibrosis I asked my doctor to change on of my blood pressure medicines to it which he did, coincidently on that visit he detected some fibrosis by feeling the stiffness of my liver. The hepatic stellate cells (HSCs) are activated into myofibroblast-like cells that produce the fibrosis by angiotensin II.
Avatar m tn The mechanism of action of Campral® (acamprosate calcium) Delayed-Release Tablets in maintenance of alcohol abstinence is not completely understood. Originally, several neurotransmitter systems, including GABA, were investigated for a possible role in Campral's mechanism of action. However, recent evidence suggests Campral's main interaction is with the glutamate system. Chronic alcohol exposure is hypothesized to alter the normal balance between neuronal excitation and inhibition.
Avatar m tn http://www.nasdaq.
Avatar n tn I tried to talk to my husbands P.A. about Losartan (Cozaar) and she just kind of blew me off. If we actually got to see the Dr., he would probably discuss it with us but she doesn't even want to hear about it. Joe has esophageal varicies and Nadolol is what they think is best. I read a study that showed an increase in platelets and albumin levels and subjects with liver disease. I will be watching the news on this.
Avatar m tn Oyakawa I am in my 3rd year of medical school and I was wondering the mechanism of action of steroid injections in the eyelid causing cataracts. It is not an osmotic agent so why does that occur? thanks so much.
382218 tn?1341181487 Thanks for posting this DV. My favorite part was the mechanism of action for Tecfidera. "Poorly understood...
Avatar f tn Plavix has a unique mechanism of action by blocking the amplification of platelet activation by released ADP, and often used with aspirin to prevent the risk of clots for the first year after DES implant. Plavix and aspirin have different mechanism of action to prevent clots. After a year, plavix is usually discontinue as the risk for clots is decreased, and aspirin is continued long term. The risk of a clot is about 3%.
Avatar m tn Losartan is a really good drug with few side effects. 50 mg is not a high dose. It should not be causing any of the problems you mention. Ask your doctor.
Avatar m tn //www.drugs.com/sfx/losartan-side-effects.html Uncommonly, ear congestion and hearing loss occur. But you are describing hypersensitivity. Losartan is associated for some with tremor. I would wonder if the sound issue is not related to a bit of anxiety. I'm not really seeing anything in the literature to support what you describe with retards to sound being louder but sensory experiences can be affected whenever our nervous system is not regulated.
Avatar m tn His averaged blood pressure is 146/80. He was placed on losartan potassium (50 mg) for 8 days but there is no change to his averaged blood pressure. Would you advice him continuing losartan or seek new drugs? Many thanks. Read more: Hypertension : Losartan Potassium - High Blood Pressure and Hypertension Forum - eHealthForum http://ehealthforum.com/health/hypertension-losartan-potassium-t488636.
Avatar n tn There are ones that have different times of day as well as the days of the week. I recommend you get one from you local pharmacy and lay out your blood pressure medication in it for each day. That way, like a parent of mine has done, you can look at your container and discover whether or not you forgot to take your pill.
Avatar m tn I am having a very difficult time w dry mouth and sometimes feel like I cannot swallow either
1008841 tn?1293598960 rank=1 I don’t know if a letter to the principals of this study would yield any information about either the efficacy or availability of future trials.
Avatar m tn t even handle taking the full dose so I would split in half and be fine for a while because whne I would try to go off of it my bp would get high. I finally decided that the more I took of it the more I couldn't tolerate: feeling like I was going to pass out, leg cramps, chest pain. And not that it's been two months I think it's still working in my system. My bp is still low.
Avatar m tn HIV is transmitted by; Unprotected penetrative anal and/or vaginal sex Sharing works with other IV drug users Mother to child You never had an exposure.
16467414 tn?1448304929 I had been drinking a few Ensure that day and taken multivitamins. Both of which had higher levels of potassium in them, and when I took my Losartan, not even 10 minutes later I felt like I was dying. I ended up passing out, very lucky I didn't die. Be careful with that stuff! Even things like Powerade and Gatorade, anything that has electrolytes in it will probably have potassium! And you won't realize you've had too much until it's too late.
Avatar n tn You need to have a neurological consult and request a flicker test. There is a unique form of epilepsy that only manifests itself when there is flicker, such as watching the rotating blades of a fan or seeing telephone poles whiz rapidly by. It isn't the Losartan. The inexpensive test, which is definitive, involves a technician exposing you to a wide range of flicker stimuli. The exact etiology is unknown.
Avatar f tn Potassium is a chemical element and it is part of the electrolyte that should be in balance with other lytes to adequately conduct an electrical impulse that originates with the sinus node in the right atrium. The mechanism of action is not completely understood, but what is when a voltage (unit of potential for conduction) and electrolyte there will conduction and passage of electrical impluses.