Losartan and marfan's syndrome

Common Questions and Answers about Losartan and marfan's syndrome

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Avatar n tn I understand there is really nothing that can be done about Marfans except to monitor and treat some of the symptoms. I use a CPAP machine for sleep apnea and it is my understanding that this may retard the widening of my aortic root. My question is whether there is anything else I should do to confirm that I do indeed have this disease. Does it make a difference if I'm treating the symptoms anyway?
Avatar n tn Hi ajr81, Be sure to talk to your cardiologist about the drugs called ARBs. Please visit www.marfanlife.net, even if you don't have Marfan Syndrome, and check the thread on "losartan.
Avatar n tn Docs on here will continue to tell you about surgery and beta blockers, but will not (for some unknown reason that I'd love to hear) tell you about the latest developments in treating people on the Marfan/Loeys Dietz spectrum. I really get tired of typing this information out over and over, so I just tell people to click on my screen name and look at some older posts about angiotensin receptor blockers (ARBs) and ACE inhibitors.
Avatar n tn Connective tissue weakness appears to be at play in severe myopia in Marfan patients. As you may be aware, there has been enormous excitement in the Marfan community lately based on research originating at Johns Hopkins using ARBs (and in some studies, ACEi's) like losartan to reduce TGF-b signalling and thus arresting or even reversing aortic dilatation.
Avatar n tn I'm sorry to hear about your cousin, my thoughts and prayers are with your family. The only thing that I do know about Marfan's is that it is hereditary and it can lead to problems with the heart. I know that people with Marfan's are more susceptible to aneurysms and other cardiac problems. You may want to post on the autoimmune disorder board. I have seen people on there that have discussed Marfan's since it is considered a connective tissue disorder.
Avatar n tn Yes the reports show that it has really not changed in the interim. Aortic dilatation in the ascending aorta is any diameter greater then 3.7 cm, whereas an aneurysm is 1.5 x that diameter. Aortic surgery is usually reserved for symptomatic, rapidly expanding or large aneurysms. The cutoff for surgery varies from institution to institution and if Marfan's syndrome or a bicuspid aortic valve is present. At our institution we operate on ascending aortas greater than 5.
Avatar f tn I am a 44yr old female who was in hospital for an unrelated injury where the hospital found some irregular heart beat and sent me for an echo cardiogram. My doctor referred me to a Cardiologist and 14 months later I have been diagnosed with Marfan's Syndrome. I have a mitral valve problem. The valve doesn't close all the way properly. They are sending me for a scan of the aorta. Is the scan a CT type scan?
Avatar m tn Thank you for chosing heart disease forum for your question. Your question has had responses from previous posts and the correct forum, however, there is a new forum that relates specifically to congenital heart disorders. http://www.medhelp.
Avatar f tn Hello, I'm the mom who has a son that was diagnosed by chance with a bicuspid aortic valve and dilated aortic root at the age of 13 years old. He was diagnosed in May 2008. Initially the ascending part of the aorta was 2.6 and has progressed steadily with his six month checkups to 4.0 as of Feb 15, 2010. His root measured 3.8. He has had all genetic testing (Marfan's, Loeys-Dietz, Famial Thoraic) and they were all negative.
Avatar f tn hi all, just curious if anyone else in this group has Marfan's along with their arrhythmia? Because of the Marfan's, I'm more concerned about my heart being goofy than if I did not - the biggest worry for a Marfan's patient is that our aorta can spontaneously dissect - and when the SVT kicks in and the HR is up over 200 for several hours I wonder if that could be a problem? thanks!
Avatar f tn So I have marfan syndrome which makes me a high risk mom. Here is a brief explanation of Marfan's syndrome since its not very common; it affects all the connective tissues in my body most importantly my blood vessels and more specifically my aorta. During childbirth my aorta is at risk of tearing which is potentially fatal and for the the birth of my first I had to vaginally deliver in the cardiac ICU in case they had to do surgery.
Avatar f tn As bijoy says, there are different degrees of Marfan's Syndrome, and yeah, there is a certain distinctive type of tallness and thinness that are considered 'classic.' You can google this by putting something like 'What does Marfan's look like?' in a google search box. However, there are also a lot of things that look Marfan-ish at first glance but are not Marfan's or fully Marfan's.
Avatar f tn The doctor told me that she has Marfan syndrome and I was wondering if this is true. Could she have pigeon chest and not have Marfan syndrome? Thank you for your time and assistance with my question.
Avatar f tn Hello maggie439, The following information would be of help to you. Marfan syndrome is named after Antoine Marfan, the French pediatrician who first described the condition in 1896 after noticing striking features in a 5 year old girl. Marfan syndrome is caused by mutations in the FBN1 gene on chromosome 15,[9] which encodes a glycoprotein called fibrillin-1, a component of the extracellular matrix.
Avatar m tn By the way, Pat, regardless of whether you have Marfan Syndrome or not, you might Google "losartan" and "Marfan Syndrome" to read articles on this topic. I don't think losartan is the best ARB, but it's the one being used in the current studies. All ARBs seem to work, some better than others. Efficacy is usually dose-dependent.
Tbd I am on 20mg of Losartan and diagnosed with pre-metabolic syndrome. Anyone else in a similar shape and has some success tips for be healthy besides electronic coaching classes?
297366 tn?1215813051 Hi! Wow! That's an odd jump! Such a rare disorder. A friend of mine has Marfan's and I do know that one of the hallmark characteristics is that his "wingspan" is equal to or greater than his height. Which is no small feat (or feet), because my friend is 6' 5" !! There is a definite "look" to a Marfan's patient, as well, I'm told, tall, lanky and lean. Unusually so. His daughter is being tested now to be sure she doesn't have it.
5520965 tn?1506009040 I have two questions today. 1: In summary, I have two aneurysms; one on the pulmonary artery of 3.9 to 4.4cm, and one on the ascending aorta of 4.1X4.2cm. Add to this mitral regurgitation, overall heart enlargement and chronic chest pain (I'll get to that in question 2). I contacted my regular cardiologist to ask if I could be tested for Marfan's Syndrome, as I have not yet been, so this has not yet been ruled out.
Avatar m tn My parents are idiots and keep putting off taking me to an eye doctor. About a week ago I saw sparks in the air for no reason, just floating. Last time I went to a doctor she told me something bad about my optic nerve but I don't remember what it was. I get my eyes checked about once a year because I have marfan's sydrome and that is known to damage eyesight.
Avatar n tn I've heard of Marfan's of course but never read much about it. I just took a peek at another site and it seems Marfan's affects the connective tissue in the body. That means it affects tendons, ligaments, heart tissue/valves and blood vessels. As for questions, perhaps ask if his heart will continue to get worse, will he need valve surgery in the future, how will they manage his ejection fraction so it doesn't drop any lower.
Avatar f tn From there he developed aortic stenosis and aortic regurgitation, and his aorta began to dilate. He started taking losartan to help keep his aorta from enlarging anymore. We took him back for a check up and his cardiologist told us what my son has is rare and mainly seen in Marfan syndrome. His ascending aorta is a 2.9, at what point would surgery need to be done? He is 51 pounds. He also goes for a second opinion at Vanderbilt on May 12.
Avatar m tn After my son suffered a spontaneous pneumothorax (deflated lung) while at college his doctor there did some preliminary examinations and suggested to him that he look into learning whether he might not have Marfan's Syndrome. Wanting for my son to be able to put the issue to rest or deal with it head-on I brought to the Marfan Syndrome Center at Stanford University Med School.
Avatar f tn Andrew had mitral and aortic valve replacement surgery 2 years ago, he also had rods in his back at age 9. I am courious, are they not able to reattach his lense? Would that not work? I am also having trouble finding a good eye dr. not many drs I have run into in my hospital travels know enough about Marfans. Is this something that would need to be done ASAP or would is it able to wait 2-3 months? What type of replacement options are there and what has worked in Marfans patients?
Avatar n tn Well, I'm assuming the echo showed normal wall motion, cavity sizes and ejection fraction - which would all be very positive indications of heart health.
Avatar m tn He likely has Marfan's Syndrome. It is a very complicated surgery and usually requires the cooperation of a retina surgeon and a cataract surgeon. Problem with waiting is the eyes may not develop properly and get reduced vision (amblyopia) This is often done best in university medical center with pediatric anesthesia and pediatric ophthalmologists.
336017 tn?1263579257 The difference in aortic root sizes is probably related to the different measuring tools used, echo versus CT. When there is a difference between the two, CT is often preferred as its measurements are orthogonal to axis of the vessel being measured. There likely was some distortion of the aortic sinuses with surgery, and this may the cause of the remainder of the difference. More importantly is do you have Marfan's syndrome? Has anyone checked for the presence of the phenotype?
Avatar m tn Well, Lincoln supposed suffered from Marfans and I know he also suffered from 'melancholy',and back then they had no inkling of BP. Have you done any indepth research on Marfan's? Not knowing you personally it would be hard to tell if it's the illness or if you have BP. I'd definitely do more research on both subjects and if you feel really strongly about the BP diagnosis I'd get a 2nd opinion.
Avatar m tn Hypertension : Losartan Potassium - High Blood Pressure and Hypertension Forum - eHealthForum http://ehealthforum.com/health/hypertension-losartan-potassium-t488636.