Sorry to hear about your symptoms. Unfortunately, Vincristine is well known to cause pretty severe PNs. Don't know what you;ve tried but I can
give you a list of things that we used here. First, capsaicin cream (over the counter
) burns when you initially apply it, but is supposed to "burn out" the
rs giving you some relief. Lidocaine patches and combo ketoprofen/ketamine patches have also be
en helpful to some patients.