Some people do experience
weight gain with
Lexapro or Celexa, but most don’t. In this case, it is not a surprise to have idiosyncratic responses, since the chemical structure of all the SSRIs is so similar.
Newer drugs, such as serotonin-norepinephrine reuptake inhibitors (SNRIs), don’t appear to have weight gain as a side effect. In fact, Meridia, a weight-loss drug, is an SNRI. Another SNRI, Effexor, has no weight-loss properties, but it is an antidepressant.