Levothyroxine pharmacokinetics
Common Questions and Answers about Levothyroxine pharmacokinetics
synthroid
- Absorption, oral: time to peak concentration 7h
- Elimination half-life = 12 h
(It says also that in general it can be administered once daily because it has a 24 h effect.Why?)
- Can you give another example to clarify it better please?
- When it says divide in 2 doses , does it mean only in the morning and dinner? 3 doses (morning-lunch-dinner)?
Thank you for taking the time to answer!!
I can't help out on the pharmacokinetics, but your reasoning is sound: it doesn't make sense to dose so that the drug runs out.
I'd query Schering-Plough as well as your hepatologist, if I were you.
Please give me a heads-up if you solve the riddle.
I have been taking levothyroxine 137 mcg once a day for a couple of years. Can I stop taking it all at once or do I gradually have to get off of it?
I posted on 6/17/2015 regarding my concerns over having had one episode of AFib and being concerned with the levothyroxine causing another episode. The only TSH info I had at that time was that my level was 5.6. This was taken on 5/7/2015. I just received my lab results in the mail for blood work done on 6/11/2015. She ordered at Free T3 and T4 screening on this one. In my last post you requested the results. There was no ferritin tested and my vitamin D is ok.
Does anyone take Levothyroxine and if so, what do you think of it? I have heard different things. The doctor just got me started on meds and this is what he wrote.
just checking on others thoughts.
He was started on a 50mg dose of levothyroxine . The difference of his over all health was amazing he began to feel hungry again his breathing improved. And he was becoming more active. After about 4_6 weeks he had another repeated blood test done to check his levels and surprisingly the doctor said that his thyroid still was not functioning properly and his dose of levothyroxine was increased to 100mg. This dose made him extremely sick. Bloated . Full of trapped air. Tired and constipated.
The doctor put me on Levothyroxine, and now after 3 and a half months, I have indigestion approximately 3 times a week, bloated stomach, and balance problems. Why should I take this medication when before I started taking it, I had no symtoms? Can I stop taking this medication? I'm thinking that perhaps I was born with this thyroid problem, and it was not a problem until I started taking the medication.
ive missed my medication. levothyroxine for 10 days. what side affects should i experience? i feel lethargic and have been vomitting ? is this to be expected?
Hello, I was diagnosed with thyroiditis and after going from hyperthyroidism to hypothyroidism I was put on 75mg of levothyroxine than my doctor said to only take half a dosage and now I've been off the medication for 6 days I was supposed to be done with treatment but ever since I stopped the medication I've been feeling dizzy again and exhausted my hair is falling out again my hands are shaking I have cold feet and nausea I told my doctor but he says I'm fine I was wondering could
without know you history I will say that you need to be on the levo for the rest of your life
Your dose needs tweaking from time to time You realy should be have blood testsdat least every 3 months.I would suspect your illness is not from the levo but your dose needs to be tweaked and get you on the right dosage.
In my case I have lost 22 pounds and I was on too high a dosage so I had blood labs and sure enough I needed to lower my dose of the levo.
I have been taking levothyroxine for 4 months now. Will I see any boost in my metabolism soon? I have been trying to lose weight, and can only seem to take of pounds (5 in 9 months) by doing excessive cardio (2 hours per day). I am eating between 1500-2000 calories per day and sleeping a lot, like 9 hours every night. Is there any hope or piece of mind for me?
my doctor told me that i have hyperthyroidism and put me on .05mg of levothyroxine to start with. i have read about alot of side affects and am worried about the hair loss and weight gain the most. anyone on this medication and can give me some feedback that would be great. i am already overweight, at 170 now i have gained almost 40 lbs in 4 years. my left eye is also larger than my right, she said it will get better with time.
My dog has had hypothyroidism for several years and has been on 0.2 mg of Levothyroxine twice daily ever since. Recently, when they did a check on his T4 they found that it was low and they increased it immediately to 0.4 mg.
A week or two later he began to significantly pant and wheeze. Then he decided to give him 150 mg of Theophylline twice daily. Could the thyroid dose change have caused these symptoms or is it a coincidence?
My dog has had hypothyroidism for several years and has been on 0.2 mg of Levothyroxine twice daily ever since. Recently, when they did a check on his T4 they found that it was low and they increased it immediately to 0.4 mg.
A week or two later he began to significantly pant and wheeze. Then he decided to give him 150 mg of Theophylline twice daily. Could the thyroid dose change have caused these symptoms or is it a coincidence?
Do I take Levothyroxine when my TSH is 0.66, total T4 is 5.6 and T3 uptake is 33.4%? I think I might be hyperthyroid, not hypothyroid. I have to take metoclopramide for stomach dilation and I take Diazapam plus other meds on the very long list of containdicated medications. Does anyone know?
I was diagnosed with hypothyroid less then a week ago and started taking Levothyroxine 50mcg and 2 hrs after I take the meds my heart races and feels like its literally going to pound its way out of my chest. I phoned my Dr with my concerns and she told me that it takes time for your body to adjust and to keep taking it until I'm re-tested in 6 weeks. My chest now hurts and I am afraid to take the meds. Anyone else have this issue?
I started taking levothyroxine as my doctor thinks I could be developing hypothyroidism. I have taken it now for two days, is it normal to feel fluish symptoms and have headaches/achy feeling? If so how long can I expect it to last.
whats the best time of taking levothyroxine tablets have been taking at bed time and i have gained weight
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