Levaquin and warfarin interactions

Common Questions and Answers about Levaquin and warfarin interactions

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Avatar n tn I have been on Coumadin for 18 years due to Lupus Anticoagulant (Antiphospholipid Syndrome) and several DVTs. In 2005 had MI with occlusion of the LAD artery and had drug stent inserted and I am still on plavix. My doc has debated when to take me off the Plavix safely....what are the recent studies about this dilemma? thanks so much!
Avatar m tn Enhanced hypoprothrombinemic response to warfarin has been reported in patients with acute alcohol intoxication and/or liver disease. The proposed mechanisms are inhibition of warfarin metabolism and decreased synthesis of clotting factors. Binge drinking may exacerbate liver impairment and its metabolic ability in patients with liver dysfunction. The risk of bleeding may be increased. Conversely, reductions in INR/PT have also been reported in chronic alcoholics with liver disease.
Avatar n tn To date there have been no reports of an important interaction in humans between warfarin and clopidogrel. Nonetheless, because warfarin increases the risk of bleeding, blood tests to measure the degree to which the blood is anti-coagulated or thinned (prothrombin time; INR) may be ordered to assess the degree of blood-thinning when warfarin and clopidogrel are used together.
Avatar m tn you have to think of the worse case senario of switching to warfarin having the warfarin be too strong and your wife getting a bleed of some kind. This could be in her GI track, brain etc. and can be very life-threatening and could cause huge hospital bills. So, depending on how long she will have to take the plavix for, and what she is taking it for, it may actually be less expensive to use the plavix.
Avatar f tn Loading doses of warfarin are not warranted and may result in bleeding complications. Interactions with other drugs must be considered, and therapy in elderly patients requires careful management. Current dosing recommendations are reviewed, and practical guidelines for the optimal use of warfarin are provided". Hope this helps, and if you have any further questions or comments you are welcome to respond. Thanks for your question. Take care.
Avatar f tn My INR will not go above 1.5/1.6. And yes, I know all about the Vit K interactions and anything else that is possible to Google about interactions.
233622 tn?1279334905 The clearance of R-warfarin is generally half that of S-warfarin, thus as the volumes of distribution are similar, the half-life of R-warfarin is longer than that of S-warfarin. The half-life of R-warfarin ranges from 37 to 89 hours, while that of S-warfarin ranges from 21 to 43 hours. Studies with radiolabeled drug have demonstrated that up to 92% of the orally administered dose is recov-ered in urine. Very little warfarin is excreted unchanged in urine.
179856 tn?1333547362 Nygirl, When I was on treatment, I got sick and my neuts fell to zero, I was on IV levaquin for 15 days and went home with oral levaquin for a few more weeks. I have cirrhosis. My liver enzymes didn't even budge. I think you will be ok, too. While we have to be cautious and make sure our docs are doing the right thing, many of those warnings are weighed against the benefits of taking the drug.
Avatar m tn ve told us that you are not on an anticoagulant such as Warfarin). The most serious threat we AFib sufferers are exposed to is clot formation and the possibility that will cause a stroke. Aspirin will reduce the risk, an anticoagulant will reduce the risk further.
Avatar n tn In a conflicting report, the effects of acute and chronic dosing of APAP on warfarin pharmacokinetics and pharmacodynamics was studied in 20 healthy males in a 2-phase, randomized, crossover study. The mean serum concentrations of S- and R-warfarin did not differ significantly between treatments. There was no change in anticoagulation response between treatment and control (4). INR should be monitored more closely when APAP use exceeds 2 g/day or chronic use > 7 days occurs. References: 1.
Avatar m tn I am concerned about possible drug interactions between the antibiotic azithromycin and the two heart medications warfarin and amiodarone. My relative has brief history of heart problems span one and a half years (though the underlying heart condition itself appears to be congenital). Rhythm problems resulted in CHF, hospitalization, and later diagnosis and heart surgery. Subsequent dysrhythmia and CHF has been prevented adequately with medication.
Avatar m tn Coumadin is known for having many drug-drug and drug-food interactions, which can make you over or under coagulated. For instance, since it works by being a vitamin K antagonist, foods that contain vitamin K (like leafy greens) can lower your INR. Taking vitamin E or fish oil or aspirin could raise it, and make bleeding more likely.
612551 tn?1450022175 I have been taking 2 grams of Korean Ginseng for a few months now and have found no problem with interactions with use of Warfarin. I not here for experience here. I take mostly in the hope to achieve some energy improvements, none noted, but fyi, I lost about 10 pounds down from about 238, I am 6' 5". I believe this may be due to the Ginseng affect on my digestion of carbohydrates (which I love to eat) - causing less production of blood sugar and fat.
4822967 tn?1367656696 I did check the drug interactions between methimazole (Tapizole), carbimazole and PTU (the three major ATMs...anti-thyroid meds) and warfarin. While interactions are listed, it appears ATMs enhance the blood thinning effect of warfarin. The warning was that warfarin might have to be lowered once on ATMs. Not the best situation, but given the alternatives... Are your going to do the RAIU despite the iodine?
Avatar m tn t know how warfarin is affecting your life style. I have been on warfarin for years and had no concerns about running and bike riding, and using power wood working tools. All of these activities puts one at an increased risk of a cut and bleeding, but I simply take the risk. On the other hand, I don't sky dive, or pick fights ....
Avatar f tn I take propranolol for pvc's. I had been sick and a dr prescribes anantibiotic(forget name) and it caused me to have such pvc,s I think I almost died. I was I think on my way out when my cat jumped on my chest, and started my heart to beat. Went to the ER, the ekg was showing ovc's on top pf pvc's and the dr said my heart was spasming, and I was having chest pain and sob, because oxygen was not getting to heart......now I am paranoid.....should I have more tests?
Avatar n tn Recently I saw my MD and she ordered several blood tests and MRI to look for MS and other peripheral neuropathy causes. All blood tests and the MRI were normal. I think that I have had a severe drug reaction and do you think the shooting pain is Levaquin related? I took Ibuprofen for the tendon pain for 2 years starting the day after I finished the Levaquin 3 years ago. Did this increase the nerve damage? I have no balance or muscular strength problems.
Avatar n tn ginger and glucosamine sulfate will affect coumadin (warfarin) I'm on warfarin and can't take ginger or glucosamine and a host of other supplements.
Avatar f tn DOES ANYONE KNOW IF WARFARIN CAN LOWER YOUR BLOOD COUNT AND AND ALSO LOWER CALCIUM AND VITAMIN D LEVELS?
690060 tn?1247841741 s been making its way to FDA approval, which was finally given today. No INR monitoring, no food interactions. But cost might be $10/day rather than 10 cents. https://us2.ixquick.com/do/metasearch.pl?
Avatar f tn Seven months ago I had a pulmonary embolism and I am told this may have been the second one.I am taking 7 mg of warfarin a day and my INR is 2.5.I had a liver transplant 10 months ago,and was told my vascular system was not great.Given my overall situation I am concerned about heart attacks and strokes.Do you think I should be taking 75mg of aspirin a day as well as the warfarin?Thanks.
Avatar n tn She has been on warfarin and monitors it regularly. She also has past history endometriosis and has always had heavy periods and problems with her periods. She also has uterine fibroids that have been giving her problems, even more so since the warfarin. Between the uterine fibroids and the warfarin, her menses are extremely heavy. She is on iron because she tends to be anemic around her period. Her periods are so heavy that she can go through 4-6 large pads an hour, sometimes more.
612551 tn?1450022175 CoQ-10 is frequently recommended for reducing side effects in patients taking statins ( like Lipitor) and I haven’t heard of anyone on warfarin having issues. I would recommend consulting your doctor first (obviously) and maybe refraining from COQ-10 unless you have some nasty symptoms that you absolutely can’t tolerate which COQ-10 has been shown to alleviate.
Avatar m tn I believe it could be a FATAL mistake if you stopped taking the warfarin. Mechanical valves will clot without warfarin and this could cause a heart attack, stroke or heart failure and could cause you to have to have another open heart surgery. PLEASE ,PLEASE talk to your doctor about any changes in the warfarin.
Avatar n tn A drastic change in diet can alter INR also, but in my own personal experience, it has usually been other meds that caused me to need to change my warfarin dosage and not my diet. An INR that is consistently out of range is dangerous. Don't worry about maintaining the same dose of warfarin. Worry about maintaining an INR that is consistently within range. Whatever dose of warfarin you have to take to stay in range is okay.
Avatar f tn Sometimes aspirin is used in place of the Plavix, and the patient will be on aspirin and warfarin. That type of combo regimen is used when the doctor doesn't think that one drug alone is enough to do the job, and one drug obviously wasn't enough in your case. It seems that your Plavix and warfarin regimen is working, so I'll join you in giving thanks for that.