Leflunomide liver

Common Questions and Answers about Leflunomide liver

arava

taking drugs like leflunomide 20 mg per 24 hour. since last one month.fiteen days back i tested sgot level 24 and sgpt level 33, which rose to 61 and 85 respectively after 20 days i.e tested on 27-07-09.though having no adverse symptoms of any kind. medicines being taken madrol 4 mg daily , Methotraxate 2 mg. per 50 ml. (8.8 ml weekly injectible subcutaneous). non steroidal antiinflammatory 2000 mg. per day.eltroxin 150 mg per day, calcium + antioxidants.
I am now on Leflunomide instead of methotrexate and prednisone. I am having terrible flatutence and severe gas with anything I eat. Is it ok to take Imodium to lessen the symptons each time I eat? I will be going to my Rheumy next Friday but wanted to see if others have had this issue? Your advise is appreciated.
Aubagio (pronounced oh-BAH-gee-oh) is a novel oral compound that inhibits the function of specific immune cells that have been implicated in MS. It is related to leflunomide, a drug used to treat arthritis. Aubagio can inhibit a key enzyme required by white blood cells (lymphocytes), reducing the proliferation of T and B immune cells active in MS and also inhibiting the production of immune messenger chemicals by T cells.
You will need regular blood tests, including liver function tests. Leflunomide must not be taken during pregnancy because it may cause birth defects in humans. Methotrexate This drug can be taken by mouth or by injection and results in rapid improvement (it usually takes 3–6 weeks to begin working). It appears to be very effective, especially in combination with infliximab or etanercept.
The good thing is my internal organ esp. my liver is clear meaning no fatty liver. But, need to monitor because of the counts. Before, he prescribed for any medication, he advice to make a research regarding the medicine that he probably prescribe and notes all the side effects. You must read the AASLD Guidelines, after i understood the flow and the side effects, he made me decide of which medicine im going to take.
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