Leflunomide and methotrexate

Common Questions and Answers about Leflunomide and methotrexate

arava

I was on methotrexate (MTX) for more than 20 years (10 years on the tablets and 10 years on the injectable) and it served me well. My doctor said I had to take a break from it in 2008 and just took me off it altogether with no replacement. I suffered few side effects from the withdrawal of MTX and have been getting along fine with a few over-the-counter painkillers and tramadol ever since.
I was on methotrexate since 2009 and now I am lactose intolerant. I just can't seem to eat anything with dairy even with the dairy supplements to help ease the symptons. Has anyone else had this problem? I just got changed to leflunomide daily. WIll I get any better with this medicine? Thanks in advise for any suggestions.
I have read too much bad stuff about this medicine and I am hoping someone has had a good experience with it. I have tried methotrexate and Diclofenac, but now I am just on the Diclofenac and the Arava. Hope everyone is doing well.
Though non steroidal anti-inflammatory agents (NSAID) and steroids are the gold standard of treatment, more emphasis should be laid on physical and occupational therapy, rest, heat pads and use of assistive devices for walking. Both NSAID and steroids should be used with caution given your age and weight loss and gastric history.
I am now on Leflunomide instead of methotrexate and prednisone. I am having terrible flatutence and severe gas with anything I eat. Is it ok to take Imodium to lessen the symptons each time I eat? I will be going to my Rheumy next Friday but wanted to see if others have had this issue? Your advise is appreciated.
hi was just reading your post there i have severe psoriatic arthritis deformed fingers and toes all my fingers have seized completely with arthritis and some are bent over to the side , i was on remacide for 5 years and it made a dramatic change to my life from severe pain to none what so eber i had an iv every 7 weeks of remacide until march this year i woke up with numbness in my left leg which over a few days travelled up my side and face went for an mri and a few months on was diagnosed with
I am now on Leflunomide instead of methotrexate and prednisone. I am having terrible flatutence and severe gas with anything I eat. Is it ok to take Imodium to lessen the symptons each time I eat? I will be going to my Rheumy next Friday but wanted to see if others have had this issue? Your advise is appreciated.
I was put on Leflunomide in Sept and lost 13 lbs or 10% of my body weight in one month. So had me get off it and rid my body of it by taking a powder for 5 days 3 times a day. Now its been 3 weeks since I was into Rheumy and did my lab work for Enbrel injections. I am now swelling, achy, and painful joints. Talked to nurse on Tues. but still waiting for a sample or my prescription but waiting on insurance and help from Enbrel. Hope all are doing good.
i have been in severe pain since last march at the moment i am on leflunomide and methotrexate this is not helping and have been offered either tocilizumab or abatacept i was wondering if anyone on the forum is on any of these meds they could let me know how they are doing thanks.
This was because I went to the doctor with pain in my knees and elbows and large bumps on my elbows. The doctor ran a rheumatoid factor test and it was positive. The doctor sent me to a rheumatologist that I saw for 5 years. I started on plaquinil, but it wasn't helpful, so switched to methotrexate. MTX made nodules go away. During the time I was getting treated wih methorexate, I had almost constant herpes outbreaks and low grade fevers. Joints got better but pain continued to get worse.
Examples would include Methotrexate, Imuran, Arava and Plaquenil. Another approach you may want to try is to have the doctor add a medication to protect her stomach and keep her on the Lefora since it is controlling her arthritis.
Hi I have Psoratric A, Rhu a & Fiber myalgia- diagnosed 2011 Have constantly taken Panodol Osteo up to 6 a day, Methotrexate 2 once a week & Cymbalta in morning but Still had pain so Rhu upped to also include Leflunomide 1 in morning & night last 4 mths also Endep 10mg 2 before bed to help restlessness ....still in pain ....so now about to start Humira but I cannot afford to gain weight,, and the forum makes me afraid to take.......as met have a few years ago ...
He has been using methotrexate and leflunomide for about a year. The purpose of using methotrexate is to suppress his immune system. So his immune system now is much weaker than normal people now. He also had some canker sore on his mouth last year, but never on his tongue,, which was believed to be the side effect of using leflunomide. I am very worried now because the symptom my boyfriend has is very similar to the symptom of being infected by HIV. My questions are, 1).
I did not have any symptom. My boyfriend was diagnosed with Rheumatoid Arthritis last year. He has been using methotrexate and leflunomide for about a year. The purpose of using methotrexate is to suppress his immune system. So his immune system now is much weaker than normal people. He also had some canker sore on his mouth last year, but never on his tongue,, which was believed to be the side effect of using leflunomide. My questions are, 1).
My current regimen is Humira 1wk., Leflunomide 1day and tapering off of Prednisone. But guess what?? I'm still in a lot of pain in my L/elbow and some pain in R/hand and wrist. I have come to doubt I actually have RA. Perhaps I have some weird unknow disease not known to the medical community. HELP!!!!!!!
I am about to start Humira after not getting on with Methotrexate and Leflunomide. After reading some of the post on Med help admitedly from 2008 which did not sound to encouraging is there anyone out there with more recent experiance of how you feel after taking Humira. I am looking forward to receiving Humira as I have been without any medication apart from painkillers for the last six weeks and the flare ups are happening more regular now. Look forward to hearing of your experiances.
I have read too much bad stuff about this medicine and I am hoping someone has had a good experience with it. I have tried methotrexate and Diclofenac, but now I am just on the Diclofenac and the Arava. Hope everyone is doing well.
hi thanks all for your replys, quix i was on infleximab for 5 years and as soon as i reported to them my whole left hand side went numb they stopped it this med could have been the cause of my ms being brought on but theres no proof as my mother had ms, im glad you say its one of the safer ones i saw the research from 2005 and was hopeing to see something alot newer that would be great if you find something newer it has got to the stage that i have to go on something i cant keep getting steroid
My current regimen is Humira 1wk., Leflunomide 1day and tapering off of Prednisone. But guess what?? I'm still in a lot of pain in my L/elbow and some pain in R/hand and wrist. I have come to doubt I actually have RA. Perhaps I have some weird unknow disease not known to the medical community. HELP!!!!!!!
Other meds include methotrexate, leflunomide, Plaquenil, prednisone and synthroid. I'd appreciate any thoughts you might have on the skin hypersensitivity issues.
Just within the las 3-4 months the joints in my hands PIP and MCP hurt really bad and are swollen and the skin on the joints have turned kind of red. The space in between the knuckles are really swollen also. I looked up RA and it sounds like that is what I may have. I also looked up SLE and I fit a lot of those symptoms also. The thing that is throwing me off is the discoloration of my skin on the knickles. Does anyone with RA have this? My GP is sending me to the Rheumatologist next week.
Periodic urine and blood tests are needed to check for side effects. Leflunomide This drug reduces signs and symptoms and slows structural damage to joints caused by arthritis. Bloody or cloudy urine; congestion in chest; cough; diarrhea; difficult, burning, or painful urination or breathing; fever; hair loss; headache; heartburn; loss of appetite; nausea and/or vomiting; skin rash; stomach pain; sneezing; and sore throat.
horrible left side headaches with loss of sensation on left side face and left eye pain (no redness in eye and no history of migraines previously); TMD; tinnitus that has recently increased dramatically; GERD; painful swollen joints (hands, shoulders, ankles, feet, knees, and especially cervical neck); IBS; Intersital Cystitis; insomnia; and frequent muscle cramps, including spasms in the neck/shoulder area that lock my neck at an angle, pull my shoulder back and are extremely painful.
the last and worse was Methotrexate. I gave myself a FDA pharmacy medication break and actually I felt better for a little while. Five years ago my lab work said I had Hep C. Since then I have had many blood test and a couple of major surgeries. Hep C was gone from the diagnosis and the Lupus diagnosis was back. Two years ago I had to have four vertebrae fused. I have degenative disk disease. I walk with a cane and I'm usually in pain. I accept what I have and just deal with.
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