Hi, I have PCOS and have had it for over 20 years, I also have severe PMT and I am on PROSTAP, over the last few months I have joint pain in my legs all day and at night, it is so annoying and painful, I feel tired at work and I have quite an active job, i am not lazy in any shape or form but it is really getting me down and I have been advised to lose weight, however, I find it very difficult as I also have an arthritic knee which needs surgery to a new knee, although, I can deal with the pain