Phenytoin and primidone are effective antiepileptics drugs, although phenytoin can cause
liver failure or have other harmful long
in patients with PME. Sodium valproate is an alternative therapy for myoclonus and can be use
d either alone or in combination with clonazepam.'
'Levetiracetam, a newer anticonvulsant is of
d as an add-on therapy but may be use
d alone. It has few side effects — dizziness, drowsiness, weakness — and is generally well tolerated.