Cholestasis of pregnancy, also known as obstetric cholestasis or intrahepatic cholestasis of pregnancy, usually occurs during the last trimester of pregnancy,
and triggers severe itching, especially on the hands
and feet. On rare occasions symptoms may appear before the third trimester. The condition is rarely of concern for the mother's long-term health, but may cause severe complications for the fetus baby. Cholestasis is when the excretion of bile (from the liver) is interrupted.