joint pain, flushing, redness, rosacea, depression, chronic fatigue, Seb derm,
hair loss.. even teeth breaking). I don't mean to scare you but this appears to happen too often (see acne.org). Isotretinoin was first developed as a chemotherapy agent, and to this day they don't exactly know how it really affects the body long term, hence why many are rightfully cautious about this medication.