It is true that scabies affects the fingers and webspaces but it is highly contagious and causes an intense itching sensation caused by an allergic response. Since your wife
is not having any such symptoms and there
is no intense itching as symptom, it
is less likely to be due to scabies.
The first stage of pompholyx shows tiny blisters (vesicles) deep in the skin of the palms, fingers, instep or toes. The blisters are often itchy or have a burning feeling.