Imiquimod mechanism of action

Common Questions and Answers about Imiquimod mechanism of action

aldara

Avatar m tn Our data highlight the potential of direct innate immunity activation in hepatocytes in the control of HBV replication, and support the recent interest in the development of PRR-based antiviral strategies against HBV. In addition, our data suggest that elucidation of the mode of antiviral action of imiquimod may lead to the identification of a novel target for the treatment of CHB. Disclosure of Interest: J. Lucifora: Grant: Gilead, S. Maadadi: : None Declared, O.
Avatar m tn The manufacturer of imiquimod has done a superb job of skirting FDA regulations and fostering the implication that treatment with their product might reduce the frequency of wart/HPV recurrence compared with other therapies, despite complete absence of data, and without FDA approval to promote such a benefit. The mechanism of action of imiquimod suggests a possibility of reduced recurrence rate, but the clinical experience in fact shows no difference compared with other treatments.
Avatar m tn I am not physically restricted - I walk 1 mile or more day and do 10 minutes of other light exercises most days. My BP runs under 120/80 most of the time. I understand carvedilol helps prevent stiffening of the heart muscle and can help restore LV function to some degree. How specially, so it do this? What is the biochemical mechanism?
Avatar m tn The mechanism of action of CampralĀ® (acamprosate calcium) Delayed-Release Tablets in maintenance of alcohol abstinence is not completely understood. Originally, several neurotransmitter systems, including GABA, were investigated for a possible role in Campral's mechanism of action. However, recent evidence suggests Campral's main interaction is with the glutamate system. Chronic alcohol exposure is hypothesized to alter the normal balance between neuronal excitation and inhibition.
Avatar m tn http://www.nasdaq.
Avatar m tn Oyakawa I am in my 3rd year of medical school and I was wondering the mechanism of action of steroid injections in the eyelid causing cataracts. It is not an osmotic agent so why does that occur? thanks so much.
382218 tn?1341181487 Thanks for posting this DV. My favorite part was the mechanism of action for Tecfidera. "Poorly understood...
Avatar m tn However , I have more erections during sleep (than day time ), the imiquimod cream might be wiped off by the underwear when I have an erection. In this case , Can I use imiquimod during the day instead of bedtime ?
Avatar m tn the downward trends acutally started since i tried daily imiquimod suppository oct 2012 for 7 concecutive days, hbsag down about 600iu/ml in 7 days so we cannot know for sure if maitake has a real effect anyway since there are no sides i keep it and soon i ll retry imiquimod that way for 7 days, if again i get an immediate decline of hbsag it definitely is imiquimod, if not it is just a coincidence or a sum of all the efforts i made to stimulate immune system the probability of imiquimod work
Avatar f tn Plavix has a unique mechanism of action by blocking the amplification of platelet activation by released ADP, and often used with aspirin to prevent the risk of clots for the first year after DES implant. Plavix and aspirin have different mechanism of action to prevent clots. After a year, plavix is usually discontinue as the risk for clots is decreased, and aspirin is continued long term. The risk of a clot is about 3%.
Avatar f tn The doctor performed a light cryosurgery and told me it would blister, scab and heal to remove the spot. I had the procedure done on Monday with a small blister forming. By Thursday of that week it had never scabbed and looked the same as it did before I had the procedure done. The dermatologist then had me come back in the next Monday and "froze it again" and prescribed Imiquimod daily to area for 4 weeks straight since the "freeze" was unsuccessful at removing the lesion.
Avatar n tn 3) I would like to continue applying the Imiquimod cream, but I also want to monitor my penis over the next 14 days for any signs of herpes. Is it possible that application of Imiquimod cream could delay/alter the appearance of HSV2 lesions, so that I would not know if I have acquired HSV2??? I know the blood test for herpes would not be affected by Imiquimod, but I'm wondering about the appearance of herpes lesions. Can I continue applying the Imiquimod??
Avatar m tn Surprisingly, inflammasome activation, keratinocyte death and interleukin 1 release also occur in response to the vehicle cream in the absence of imiquimod. We show that isostearic acid, a major component of the vehicle, promotes inflammasome activation in cultured keratinocytes, and so may contribute to the observed effects of Aldara on murine skin.
Avatar m tn HIV is transmitted by; Unprotected penetrative anal and/or vaginal sex Sharing works with other IV drug users Mother to child You never had an exposure.
Avatar m tn I have about 20-30 very small warts, and notice 2 or 3 of them showing a bit of redness and drying up a bit. Still not sure if this is due to the medication. Other than that I haven't noticed any effects or any type of side effects. Everything I read online says the areas should be very red/inflamed. Has anyone had a positive experience with Imiquimod without showing many effects? Should I just give it some more time or is it apparent that Imiquimod isn't going to work for me?
Avatar f tn I was prescribed imiquimod to be applied 3 days a week but heard apple cider vinegar does a great job of clearing warts. Is it a good idea to apply the imiquimod mon,wed, fri night and apple cider vinegar tues, thurs, saturday nights? Anyone tried this or have any results from either one they would share?
Avatar m tn this happened exactly when i tried daily imiquimod suppository, this probably increased immeun response of interferons and cytokines and this was the result....at the same time i also had creatinine increase to 1.
Avatar f tn Potassium is a chemical element and it is part of the electrolyte that should be in balance with other lytes to adequately conduct an electrical impulse that originates with the sinus node in the right atrium. The mechanism of action is not completely understood, but what is when a voltage (unit of potential for conduction) and electrolyte there will conduction and passage of electrical impluses.
Avatar n tn After only about 2 weeks of usage almost all symptoms of the warts were gone however I now have perianal psoriasis in its place. That is one of the side-effects of imiquimod and it mainly strikes people whom are genetically prone to having psoriasis. It is known that an overactive immune system can trigger a site of psoriasis, and imiquimod invokes an immune response to have cytotoxins destroy skin cells. So now....
Avatar m tn http://www.medscape.com/viewarticle/578705 Ribavirin improves early responses to peginterferon through improved interferon signaling. Gastroenterology. 2010 Jul;139 The therapeutic mechanisms of ribavirin for hepatitis C are unclear. Microarray analyses have shown that ribavirin increases induction of interferon-stimulated genes. We evaluated viral kinetics, serum cytokine expression, and viral mutagenesis during early stages of peginterferon therapy with and without ribavirin.
Avatar m tn Hello Dr, I'm a 26 man from China, and I had a protected vaginal sex and unprotected oral sex with a sex worker more than 3 months ago. A month ago, I find sth on my penis and went to the doctor and the doctor told me it's sebaceous which is not serious but he asked me to do a hpv test. However, the test showed I have the hpv 52 and hpv 59. The doctor gave me Imiquimod and asked me to go back three months later. Here is my question.