Hello,
Imiquimod can cause skin redness and fungal infection but it is less likely
to cause blood in semen or hematospermia. It can occur due to many conditions such as infections, swellings (inflammations), cysts, stones & other obstructive lesions, and benign or non-benign tumors of the organs of the genitourinary system (involving the bladder, urethra, the testicles, the seminal vesicles, the epididymis, the prostate gland etc).