Imiquimod application
Common Questions and Answers about Imiquimod application
aldara
3) I would like to continue applying the Imiquimod cream, but I also want to monitor my penis over the next 14 days for any signs of herpes. Is it possible that application of Imiquimod cream could delay/alter the appearance of HSV2 lesions, so that I would not know if I have acquired HSV2??? I know the blood test for herpes would not be affected by Imiquimod, but I'm wondering about the appearance of herpes lesions. Can I continue applying the Imiquimod??
ec_id=NCOMMS-20130305
Aldara is a cream used for topical treatment of non-melanoma skin cancer, and is thought to act through stimulation of anti-tumour immunity. The active ingredient, imiquimod, has been shown to stimulate toll-like receptor 7. Aldara also induces psoriasis-like lesions when applied to naive murine skin, and as such is used as a mouse model for psoriasis. Here we find that in naive murine skin, Aldara induces inflammation largely independently of toll-like receptor 7.
Ive been on aldara (imiquimod) 5% for approximately 2 months now. I cant notice if im seeing any improvement with my genital warts. However, ive developed a ridiculous rash around the application site. which is extremely red and irritated. The rash looks almost like if i ran really fast and slid my knee on a rug, except its around the base of my penis. Its sometimes itchy and i feel as if at sometimes its developing a particular scab. will this redness ever go away?
I'm 47 and was recently diagnosed with genital warts. I probably had the first one nearly two years ago,I was also going through menopause and honestly did not think much about it. Last January however I noticed more appearing. I never for a moment even thought they were warts until I saw an episode of Girls and the subject was genital warts..I began to panic and scheduled an appt with my nurse practitioner.
Hello,
For small warts , several medications(like podophyllum resin, Podofilox (Condylox), Trichloroacetic and bichloroacetic acids, Imiquimod 5% cream and interferons) are available, which can be applied directly to the surface of the warts. Other treatment options include electrical cautery, surgical removal, Carbon dioxide laser treatment and electrodesiccation. These methods are more long lasting and permanent than application of topical agents which provides only temporary relief.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC296201/
Randomized, Single-Blind, Placebo-Controlled Study of Topical Application of the Immune Response Modulator Resiquimod in Healthy Adults
DISCUSSION
Topical resiquimod gel was well tolerated when it was applied to healthy human skin as multiple doses of 1 g of 0.01% resiquimod for 24 h three times per week for 3 weeks and as multiple doses of 0.05% resiquimod for 8 h two or three times per week for 3 weeks.
Your derm is right- and too much application is not good either,you immunity being good do not worry about recurrences.
Dear doctors ,
I have a small genital wart on my foreskin and I started to use imiquimod cream recently . The instruction says that I should use the imiquimod cream during bedtime . However , I have more erections during sleep (than day time ), the imiquimod cream might be wiped off by the underwear when I have an erection. In this case , Can I use imiquimod during the day instead of bedtime ?
ve been putting a liquid on it which is like salicylic acid or something like that. It freezes up but I peel it off to put a new application. The other day I peeled it off and the white stuff came out of it. My parents have been bugging me lately saying the medicine keeps making it bigger, and they're bugged about it. But when I peeled it off and the white stuff came out, the medicine also took a chunk of the wart with it.
I have talked to several docs some use cryo but I have not found any that use laser. None even brought up imiquimod which I learned about online and feel that it might be best in my situation. It seems they prescribe whatever they are familiar with. Also a transmission question. Would my partner get the condyloma exactly where my affected skin touched theres? or could it pop up anywhere on them once they have contracted it? Also does my sperm carry the hpv virus?
Can anyone describe their experiences with Imiquimod? I am on the 3.75% cream which my doctor has told me to use every other day for a month. In the first 2 weeks, nothing happened, only just a couple days ago I noticed a very slight indication that the medication might be working, but I'm still not sure. I have about 20-30 very small warts, and notice 2 or 3 of them showing a bit of redness and drying up a bit. Still not sure if this is due to the medication.
A couple of weeks ago i discovered warts on my genital area at the base of my penis and was diagnosed formally by my dr. I was prescribed imiquimod to be applied 3 days a week but heard apple cider vinegar does a great job of clearing warts. Is it a good idea to apply the imiquimod mon,wed, fri night and apple cider vinegar tues, thurs, saturday nights? Anyone tried this or have any results from either one they would share?
If you are really concerned about outbreaks, ask your doctor about a topical cream medication called Aldara, (Imiquimod). It is exceedingly expensive and can cause a lot of discomfort, but it has been suggested that regular application can help keep the virus dormant and help you to stop spreading the disease to others.
HPV is very common. Most people carry the virus, even without visible signs. Be grateful that it is only warts and not herpes.
I was prescribed Aldara (imiquimod) to get rid of a few perianal HPV warts since cryotherapy was only making it worse. After only about 2 weeks of usage almost all symptoms of the warts were gone however I now have perianal psoriasis in its place. That is one of the side-effects of imiquimod and it mainly strikes people whom are genetically prone to having psoriasis.
2, Is it useful for me to use Imiquimod with no genital warts? Or does Imiquimod useful to help me clear the hpv virus in three months?
3, I also have an ulcers on my penis a week ago which can be seen when it's wet (it become white), and it disappear after 5 days. I kind of thought it's because of the allergy of Imiquimod. But does herpes appear 3 months after the sex?
Welcome to the forum.
Your dermatologist has much more experience using imiquimod (Aldara) than I do. We don't use it as the main warts treatment in our STD clinic and I have personally treated very few patients with it. Please confirm my replies with your dermatologist.
1) The research studies with imiquimod applied it only to overt, visible warts.
I noticed some bumps on the (left side of) opening of my anus a week ago (I have to spread my buttchecks for them to be visible) and I could feel a few more on the lining of my anal canal. I went to my physician and he told me that I have anal warts, prescribed me Imiquimod (3x a week application) and referred me to a colo-rectal surgeon. I will meet with the surgeon in a week.
If you are using imiquimod cream to treat genital and anal warts, you will probably apply it once a day for 3 days a week (e.g., Monday, Wednesday, and Friday or Tuesday, Thursday, and Saturday). Imiquimod cream should be left on the skin for 6 to 10 hours. Continue using imiquimod until all of the warts are healed,
i found this on a website.
http://www.ncbi.nlm.nih.
Stimulation with TLR7, TLR8 and TLR9 agonists did not significantly induce IP-10 or IL-6 production and, with the exception of imiquimod, did not inhibit HBV replication. Interestingly, the antiviral response induced by imiquimod was independent of innate immune activation, suggesting an additional mode of action that should be further investigated.
You can apply some calamine lotion at the rash as it will help in soothing the skin. Also wear cotton undergarments. Application of mild corticosteroid cream and oral antiinflammatories like ibuprofen/acetaminophen are also helpful. If the symptoms are severe then it will be best to consult a dermatologist
I hope it helps. Take care and please do keep me posted on how you are doing or if you have any additional doubts. Kind regards.
t shown any signs of any type of growth near or on her genitals. The Dr. prescribed me imiquimod cream which I have used as directed for the past two weeks and I have not seen any change whatsoever. Are skin tags resistant to imiquimod cream? Is it possible it is not HPV but in fact just a skin tag and the dermatologist was too quick to diagnose? Please help. Thank you.
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