I also took a bunch of Advil before I knew i was pregnant, for
a high fever
. I was worried about the Advil AND the fever
, and baby was fine with both. The biggest effect of Ibuprofen is in the last trimester. It affects the kidney/urine output of the fetus, which results in lower amniotic fluid levels. It can also thin your blood, which can increase the risk of heavy bleeding during delivery and after. Your OB will tell you the same thing.