Ibuprofen and the liver
Common Questions and Answers about Ibuprofen and the liver
ibuprofen
While in some cases it has been reported that it has result in a permanent liver damage, in other cases where the victim was taking the dose for a long and continued period it has resulted in organ failure one by one.
Some more side effects are unsteadiness, blurred vision, ringing in the ears, gastrointestinal, nausea plus vomiting, diarrhea, stomach pain, probable loss of blood in intestinal areas or stomach or both, headache, agitation, drowsiness, incoherence and confusion etc.
I'm a male aged 39.
I took a series of ibuprofen and paracetamol overdoses about 8 months ago, whereby I tool a large amount of pills. During the course of several weeks, I took about 10-15 grams of ibuprofen and some additional Paracetamol each time. I cannot remember how much Paracetamol I took. This happened at least 8 times, and although my symptoms at the time were minimal, I suffered with headaches, back ache, stomach ache and some nausea.
Studies have demonstrated that at certain dosages, ibuprofen can stress the liver and elevate liver enzymes in people with Hepatitis C. Ibuprofen must be used with extreme caution in the later stages of liver disease and for those on interferon therapy.
3. Aspirin – (Bayer, Anacin, Excedrin and others) reduces fever, relieves pain, and acts as an anti-inflammatory and blood thinner.
An amount like 10,000 is too much for the liver to absorb at one time, and there can be considerable damage that you don't realize at this time. I think you should go to a physician, relate what you have told us, and get appropriate testing. Also,maybe some therapy.....that's helpful usuallly to everyone. Keep me posted. Good luck and God bless.
This is why you have to take it several times per day when fighting a nasty headache or other pain. The body metabolizes the ibuprofen and clears it out in a matter of hours, not days or weeks. This process remains the same whether you've taken ibuprofen for two days, two weeks, or two years, unless you have liver or kidney problems.
C with Pegasys/riboviran and my hepatologist actually prescribed tylenol 250mg up to three times a day for muscle aches and pains. No doubt tylenol is hard on the liver, but because my liver enzymes were not elevated my hepatologist said that in small amounts is safe and was effective to help with the flu like symptoms.
It does not interfere with the treatment drugs but some of us have proven to be sensitive to the NSAIDs and with much liver damage, ibuprofin has some potential to thin the blood more - not good if you are already having clotting problems from liver damage.
Most doctors recommend Tylenol,used in moderation. 4 extra strength tylenols (2 twice a day) is the limit. It's a better fever reducer than the ibuprofin, anyway.
Pain management is complicated and knowing the reason why your father is taking the meds he is prescribed as well as the long-term goals and effects seems like something you have a right to ask about.
Here are a few links:
http://www.eorthopod.com/content/pain-management-medications
http://www.ncbi.nlm.nih.
Taken according to directions it should be relatively safe, and is unlikely to cause further liver damage. If you have cirrhosis, you should discuss this with the doctor; dose reduction might be required.
Narcotic analgesics are generally considered liver friendly, but of course come with their own set of issues.
I agree with the endoscopy kcee mentioned. Hep c is a liver disease and it isn't uncommon for those with it feeling the pain in this area. With liver disease many end up getting gall stones. I know when I get fluid retention I feel it in the liver where the gall bladder is more than any where else. Over the counter pain killers don't help my pain there so I can't reccomend and meds that may help. She should be on a low protien diet unless the GI directs other wise.
This past 2 weeks I was ill with the h1n1 virus. During the 2 weeks, I consumed over 50 200mg pills of ibuprofen. I have had blood work done twice (5 days ago and 2 days ago). Both resulted in increased liver enzymes. I haven't had any ibuprofen in 4 days. Is it possible that my liver enzyme increase is a result of the "overdose" with the ibuprofen. My doctor has scheduled another blood work screening in two weeks. Will my liver enzymes decrease in this amount of time?
s my understanding that paracetamol is known as acetaminophen in the USA. If that is true the two are a bit different acting analgesic and should not interfere with one another. Please don't take my word for it.... you need to consult a professional on this question. There may be reasons these two should not be used together in your situation..... Please consult your Pharmacist.
Best of Luck to You.
Sweetie, there is nothing that you can take that is "a night time formula" that would have that much Ibuprofen in a dose. You shouldn't exceed the recommended dosage and if you took something that said it was a night time formula then you probably took something with diphenydramine in it. What are the active ingredients on the bottle? What strength per dose? 2900mg of Ibuprofen plus anything for sleep in not good. You need to tell someone what you took before you go to sleep.
Tylenol is perfectly safe and will not harm the liver in the recommended doses. It is overdose that cause problems, and they can be serious to the point of fulminate liver failure requiring transplant, or even becoming fatal.
NSAIDs, on the other hand, are not good for long term use. My doctor has steered me away from them.
The active narcotics in the pain reliever (hydrocodone, for Vicodin and Lortab) are not harmful to the liver as far as I know.
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