Narcotic (opioid) analgesic agents are extensively metabolized by the
liver,
and several of them (e.g., codeine,
hydrocodone, meperidine, methadone, morphine, propoxyphene) have active metabolites that are further converted to inactive substances....."
Opiates can cause liver damage, some more than others. I wish I had better information for you. I encourage you to discuss this with your physician. .... and Please let us know how you are doing and what you discover.