In the validation set, HA was accurate in predicting significant
fibrosis, severe
fibrosis,
and cirrhosis with AUCs of 0.73, 0.77,
and 0.97, respectively. Moreover, accurate HA level cut-offs were defined for predicting significant fibrosis, severe fibrosis, and cirrhosis. Thus, the study supports that HA level may be clinically useful as a non-invasive marker for liver fibrosis and/or cirrhosis.
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