I take a nitrate (isosorbide) for more than 6 years 3 times before going to gym for workout. My blood pressure
does not drop between intervals...in fact I was told to have intervals of nitrate free period. It is true, nitro dilates the coronary vessels and prevents angina (chest pain). The patch should only be worn for up to 12 to 14 hours a day, or as directed by your doctor, but continued use with no interruptions can cause a tolerance for drug....