How does nitroglycerin work in the body

Common Questions and Answers about How does nitroglycerin work in the body

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To be honest it doesn't really seem to always work and I am too scared to take the second shot in case that doesn't work either. So i try to "will" away the pain or bear it until it goes. My question is, how many times a day can I safely use it or at what point should I go to the hospital? There are no guidelines other than if it doesn't work after 2 consecutive shots, go to the hospital. Also if the nitro isn't working, is it really vasospastic angina?
Does not interfere with walking or movement, but my internal medicine doctor said my grip was slightly less on my left side than right, and my left eye, when looking all the way to the left, seems very slightly shaky. -Heaviness in left side of body, mostly in leg. Again, this does not have an affect on my walking or balance. -Vibrating sensation in body. Mostly in foot. Sometimes in abdomen and chest. Comes and goes it seems, or maybe I'm just not noticing it at certain times.
if we suppose that the patient does *not* faint during a tilt-table-test, how long is each position supposed to last? And the second is relating to the tracing of the syncope event: http://img.photobucket.com/albums/v600/bluewind95/TTT6-SMALL1.png <--- That's a scan of the tracing, and my attempt to enhance the contrast to actually be able to distinguish the tracing lines (I guess the machine was running out of ink?) left two very visible blotches on both sides of the scan.
) CHOLESTYRAMINE (in Questran) may interact with LEVOTHYROXINE (in Levothroid) When these drugs are used at the same time, cholestyramine may combine with levothyroxine in the stomach and prevent it from being absorbed into the body. If this happens, then potentially less levothyroxine would be available for the body to use and blood levels could become too low. This could make levothyroxine less effective in correcting hypothyroidism (also referred to as an "underactive thyroid").
He also mentioned that I could have a surgery done where they would go in and cut a part of the muscle and it would relieve some of the tension causing the fisher. BUT I don't know if I am ready at 32 for the side affects; except today I was seriously considering it. Side effect like not being able to control you bowel and wetting yourself and letting air out without knowing.
5 mg ( first was 5 mg ) Ormocor and 80mg Lipitor. I get pains in my chest in the heart/sternum area esp., when I wake up in the morning or Ilean to one side or twist my upper body. The pain is sharp but appears and ends abruptly lasting a few seconds. Other then this I have done 10 mile treks, walk 3-4 miles most days, sometimes jog, walk up steephill at a brisk pace every other day. Sometimes walk up the stairs 30 times, which gets my sysyem going but don't suffer any pains.
ive been to the er umteen times they tell me my EKG turned out fine my blood work turned out fine my Xrays turned out fine ..why does this little thing in the back of my brain tell me otherwise..i have a friend that was 32 and 7 months pregant with her first little boy .she had a sudden heart attack on the 18th of last month .she didnt make it through and neither did her son...so now im really paranoid about my pains now .
Also at my worst I have been physically sick but this hasn't happened (the being sick)for years I think it as something to do with me having learnt over time how far I can push myself before I end up in bed for up to 2 wks as I have in the past, although I still end up ill in bed more often than I'd like, it doesn't last as long as it would have when I used to push myself too far. Does anyone else have these symptoms or anything like them wether diagnosed or not?
Now that I'm on this medication, the heart rate has decreased a bit, I was at rest at 104 now it's at 90 at night it goes to 77, and the chest pressure I was feeling that is gone. My question is, how long would it takebefore the meds control my blood pressure?
Then three days later the symptoms worsened and the patient visited ER. The attack was initially three days ago, but how could this be deducted by the troponin?
Before a new, good MD came to this conclusion (I had seen several docters before this last one), I had suffered terrible pain in my upper abdomen, in the middle and slightly to the right side, and some what in my back, accompanied by hot flashes, sweating, and eventuallly, but not always, vomiting. Also white colored bowel movements could happen the day after an attack. After many tests(x-ray, ultrasounds, CAT scan, ERCP which caused pancreatitis, etc.,..
I have muscle spasm in or around the ribs on both sides (in the front under the breast and sometimes in the back at the same horizontal position), it feels like a ball rolling, in that it switches sides. It occurs even at night during sleep, painful enough to wake me. I only know that when I relax and stretch (the side where the knot is) using several positions I have to wait till it goes away, in many cases to have it return in other places described above.
The heart's primary job is to circulate freshly oxygenated blood to the brain and other organs throughout the body. To keep healthy, the muscle that does the work needs some of that blood too, and it is supplied by the coronary arteries. Blockages in those arteries starve the muscle of oxygen, leading to chest pain. Major obstructions in the large vessels often causes a heart attack.
These receptors are distributed in various locations within the spinal cord and brain structures. Figure 1 shows the distribution of opioid receptors in the brain of a guinea pig. Mu opioid receptors are highly concentrated in the outer laminae of the dorsal horn of the spinal cord, whereas delta opioid receptors are diffusely distributed throughout the dorsal horn (Quirion 1984, Quirion et al 1983).
The rare but familiar sharp, quick spasms that go up the heart to jaw and thru to the back I assume involve the LAD. The spasming in the microvessels seem to be the chest tightening and SOB that can accompany this. Still no research on this as to cause or treatment. I'm just happy that I pull out of these episodes, tho' very tired, with the nitro sprays. I am still wearing two 0.6mg patches daily 24/7. February 2010: Now I'm up to 0.16mg daily nitro patch and two calcium channel blockers.
I had our son in the middle of the night in front seat of our brand new pickup truck on a ferry in Galveston. The severe abdominal pain started again once my son was born. We moved several hours away, and I had to find a new OB/GYN. One year later I had a positive pap and ended up having a biopsy of my cervix and then cryosurgery. The doctor was very cold and didn't even give me anything for the pain. When I told him about the painful bm's he said I needed more fiber.
It causes me to have spasm coughing and if I cannot control this to 3 or 4 coughs my windpipe closes over making it hard to breath in or out. The last one about 2 years ago stopped me breathing in and out completely for 10 to 15 seconds and I thought I had bought it. The spasm cough causes it all and when it goes away (usually 4 to 5 days) things are relatively normal although a normal cough stays with me for weeks after.
It does get worse with some foods I eat, but usually is a constant pain and feels feel somebody has jabbed me in the side right under the rib cage. The doctor down at MUSC states that it could be Sphincter of Oddi dysfunction but all of the blood work that I have had done does not indicate that, so I have become a guinea pig for medicines.
It doesn't take a medical degree to work out that anything that affects the nervous system can affect any organ in the body, including the heart, so the chances are there is a link. Is there any way you can stop the stimulants for a while or is that not feasible? Of course don't do anything without talking it through with your doctor. I would be interested to know where in your brain lesions are. I am undiagnosed, maybe don't even have MS, but have white matter brain lesions.
I know this is going to sound crazy...Do you know what an esophageal spasm is? The next time this happens, try drinking (I mean chugging!) a glass of ice water...If it stops it, it's "diagnostic", the theory being the spasm is "shocked" into stopping...Nitroglycerin sometimes works on it too...I'm in agreement with medchick.
if you drink a glass of water when the pain starts, does it lessen for a while? If it does, the problem could be esophageal reflux disease. It can hurt very fiercely and even cause dizziness and breathlessness. In any case, your doctor should do some tests to see what is happening. Has the doctor done any tests at all other than blood work? Is he/she having you take iron because you are anemic? Have reasons for the anemia been explored?
I thouth I found a great cardiologist who understood Dysautonomia and even referred me to Vanderbilt so I can have more testing since it wasn't his expertise. Boy was I wrong, when push came to shove and I gave him my RFC form and restrictions/limitations about everything I'm going through his response was - I can't sign this - there is no reason with these conditions why you shouldn't be able to work or be medically "disabled" How do I get a doctor to understand?
I also have muscle twitches all over my body all the time. The only place where i get painful spasm is in the chest though. That's why i would still love for someone to answer my 2 questions in my initial post.
About six months ago i started having these stabbing chest pains out of nowhere, very quick in the center of my chest and/or extending to both shoulders. then following they started becoming more frequent and severe, i went to the E.R and had some blood tests done as well as an x ray and ekg. i was told i was fine and just had anxiety. since then my symptoms have been worse.
We are talking about forcing the arteries fully open here, and not how the body 'normally' would function. It is not normal for every artery in the body to suddenly fully dilate and has nothing to do with gases or beds. I presume you mean CO2 by the way? not carbon oxide? When all arteries are fully forced open, an increase in heart rate will definitely increase blood pressure. It isn't a misconception, it's a fact.
Desertrat49, I was diagnosed with a 4.2cm ascending aortic aneurysm in January 2005. My life fell apart after the diagnosis. I couldn't think at work, felt depressed and just knew I was going to die at any minute. About a month after the diagnosis I had an attack of afib and was put on Toprol. I continued to have bouts of PVCs and PACs which I attribute to stress.
The numbness still comes and goes threw out my body i am scared that it will become permant too. I also, had ekg done in 2006 the doctor said he saw some vegetation or maybe a thrombsis in my right chamber of my heart. The same doctor who read the report said this is what he saw so i saw him again in his office for another ekg which was ok then. He wanted to do a scope down my throat but i was really scared. I will never really no what the echo read.
some dr's do a full tilt up and some only like a 90degree like my dr - they keep track of your hr/bp and then after about 20 min if you haven't fainted they may give you a dose of nitroglycerin to see how your body reacts; if you faint they put you back down quick and put your knees up to get your stats back up quick the ep study is a bit more complicated; but realitively simple - some dr's sedate some don't; it depends on if they feel like they can trigger your problem easily - sometimes they
One in August, the other in October. In the beginning of november I experienced chest pain and went to the hospital. A third catheterization was done and showed my 2 stents were fine as is the rest of my heart. No constricted vessels or blockages. They tested me for stomach and esophagus problems. Checked my gall bladder and pancreas and was told that I have a little GERD. I was sent home on a nitro patch. Was already taking plavix and lopressor since august (1st stent).
The physician will usually (although not always) want to study the esophagus in its natural state. In other words, there should not be any medicine in the body that can affect the function of the esophagus. The physician informs the patient what medications should and should not be taken. The following drugs may affect the contractile pattern of the esophagus. They usually need to be discontinued at least 48 hours beforehand. Check with your physician about all your medications.
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