However, there is a 20–35 percent chance of recurrence, depending on the histologic grade. Recurrence is usually treated with further
surgery, either another local excision or a complete mastectomy.There is no way to prevent phyllodes tumors because their cause is not yet known. Other than surgery, there is no cure for phyllodes, as chemotherapy & radiation therapy are not effective. (http://en.wikipedia.org/wiki/Phyllodes_tumor)
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