The first stage of pompholyx is acute and presents as itchy blisters
on the hands, fingers and toes
. Then the chronic stage shows more peeling, cracking, or crusting. Then the skin heals up, or the blistering may start again.
In exfoliative keratolysis, the first sign is one or more superficial air-filled blisters on the fingers or palms. The blisters burst to leave tender, circular areas. The symptoms are aggravated by exposure to irritants including water, soap, detergents and solvents.