Graves disease is caused by
Common Questions and Answers about Graves disease is caused by
graves-disease
I went off my med and within 2 weeks I was feeling like my old self again. If the TSH is very low and the Free t4 is on the high end of normal he is defintly overmedicated and that could be the problem. I went to see and endo last week and we changed my med from 88's to 50's. What a difference it has made.
Good luck...
You are saying that after tow RAIs and almost a year after the last RAI, you are not on thyroid medication(?) Aren't they getting the RAI dose right(?) Although I have heard of up to 5 RAIs done safely - must be a tough thyroid. ;)
Thyroid eye disease, like Graves' hyperthyroidism and Hashimoto's thyroiditis, is an autoimmune disorder. It is caused by the reaction of antibodies and certain white blood cells called lymphocytes.
What symptoms did you have when your TSH was 0.0001? Was TSH the only thing that was tested? Suppressed TSH doesn't necessarily make one hyper unless you have hyper symptoms with it, which presumably you did, since you had to go to the hospital. My TSH has been < 0.01 for the past 6 yrs and I've never been hyper.
I'd ask the same questions about symptoms and other tests being done when your TSH was 277. What symptoms and what other tests were done?
The double posting is probably not your fault. We have a members' forum (this one...you're right, we're all patients...no doctors monitor this forum) and an expert forum, where you can ask a doctor. The problem is that there are so many questions posted to the expert forum that they only take so many per day. Some or all of the rest of the posts are referred to this forum by MH.
I think your two antibody tests, TPOab and TGab, were both negative.
s causing your hyperthyroidism? Do you know if you have Graves Disease, which is most often associated with hyperthyroidism.
What, if any, lab tests have you had done? You should, at the very least, have TSH, Free T3 and Free T4 done... if you have results for those, please post them, and be sure to include reference ranges, as those vary lab to lab.
If you've had any antibody tests done, also please include those results.
I believe the statistic is less than 50% of those who have Graves thyroid disease develop any symptoms of Graves Eye Disease. Each is caused by different sets of antibodies. Some people get eye disease without ever having thyroid problems. And, of those with Graves/thyroid who do develop eye disease, only about 5% of those ever develop serious enough eye problems (bulging, eyelid retraction, double vision, optic nerve issues) to warrant surgery.
Usually, surgery is the preferable option if someone has Graves thyroid disease (because RAI can sometimes make eye disease worse if already present). Graves Eye Disease is caused by different antibodies than the thyroid disease. They are related, but having one doesn't necessarily mean you'll get the other.
From the internet: Both Graves' disease and chronic thyroiditis (Hashimoto's thyroiditis) are autoimmune diseases of thyroid gland.
They sound like they are caused by Graves Eye Disease (also known as Thyroid Eye Disease) which is caused by different anti-bodies than the ones that caused your Graves Thyroid Disease. These antibodies cause a fat-like substance to be deposited in the muscles behind the eyes, which eventually push the eye out of the socket, causing the characteristic stare. Somehow they eye movement also causes the lid retraction you are referring to.
The antibodies can be blood tested for, I believe.
In conclusion, our findings indicate that because of low sensitivity of sonography, differentiation between Graves’ disease and Hashimoto’s thyroiditis is not possible but due to high specificity it can differentiate normal thyroid from Graves’ disease or Hashimoto’s thyroiditis. It is suggested that if thyroiditis or Graves’ disease is defined by sonography, it should be further confirmed by clinical and laboratory with laboratory data. "
https://www.ncbi.nlm.nih.
"The "Ask a Doctor" forum has been shut down since June 2014; MedHelp has not indicated whether or not they plan to reactivate it." - Wikipedia.
Excerpt from Hashimoto's thyroiditis following Graves' disease. Acta Med Indones. 2010 Jan;42(1):31-5....
"Pathogenesis for chronic thyroiditis following anti-thyroid drug treatment in patients with Graves' disease remains unclear.
All Graves Disease is hyperthyroidism but not all hyperthyroidism is caused by Graves. The key to knowing if you have Graves is to have blood tests for the antibodies that cause it - sorry, I can't remember which of the 3 anti-thyroid antibodies are related to Graves, but 2 of them are usually present. Ask your doctor if the TPO antibody test they did is the one that indicates Graves. That will give you a definite answer.
I was diagnosed with Hyperthyroidism and they did an antibody test to confirm Graves. The antibodies were positive therefore they have said it is Graves Disease ie not caused by a nodule but autoimmune. Does this test definitely rule out a nodule? I ask because I have MS and B12 deficiency which are autoimmune conditions. Would I not have tested positive for antibodies anyway because I have MS and B12? Im just worried they have missed something as they have not done a scan.
It should be pointed out that, especially in the US literature, the term ‘hashitoxicosis’ is sometimes used to describe an autoimmune thyroid disease overlap syndrome of Graves’ and Hashimoto’s disease.2 In this article the term is strictly limited to the ‘leakage’ symptoms of active Hashimoto’s disease."
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I've had both Hashi's and Graves antibodies simultaneously but I had been diagnosed with Hashimoto's thyroiditis previously.
However, when sarcoidosis occurs in patients with hyperthyroidism caused by Graves’ disease or toxic multinodular goiter, the hyperthyroidism is often resistant to treatment with I131 ablation or anti-thyroid drugs. In cases of chronic sarcoidosis, skin lesions, enlarged lymph nodes (especially in the chest cavity), enlarged spleen, enlarged liver, uveitis, cardiac symptoms, and arthritis may occur.
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