I have an appt on feb 19th,since I have been on the tapizole my pulse has been down,and my symptoms seemed under control.lately my symptoms have worsned although I take my meds everyday on time,my panic attacks have increased,I have been having muscle aches,headaches,sinus problems,sore throats occasionally.also my goiter seems to getting wider and smaller,and my eyes are always dry and they don't close all the way at night,and chest pains at times.