I'm convinced that the twice a day two scoops (55grms) of protein powder taxed my body and most likely pushed my uric acid levels off the charts causing gout symptoms. I was also eating a low cal, high protein , med. carbo diet... As I look back, the symptoms (pain, hands, wrists, feet) all started after about three Mo's of everyday use, when the pain started, I stopped the work outs of lifting and riding my bike (aerocics) but didn't stop the Powder..