Glimepiride intermediates

Common Questions and Answers about Glimepiride intermediates

amaryl

1068689 tn?1325827206 My new doctor changed my prescriptions from regular Met to Met XR and added 2mg of Glimepiride. My BG's have been above 300 for last few months and nothing seems to get them down. Doc thinks this change should do it. I've only taken it twice now but since taking it I've been dizzy. Quite enough I need to lay down. I know it says this may be a side affect but does it go away? It brought my BG's down as I said from over 300 3 hrs after eating to 180 just now.
Avatar m tn Treatment with Flavocoxid or ETV or with drugs combination started 3 hours after transfection and was renewed every other day for 5 days. Total HBV replicative intermediates, viral transcripts and cccDNA levels were evaluated in untreated and treated HepG2 cells by quantitative real-time PCR, Southern and Northern blots experiments. To analyse the epigenetic modulation of HBV cccDNA the cccDNA-ChIP assay was applied to untreated and treated cells.
Avatar m tn the drug glimepiride, is not making my blood sugar level lower; instead is higher 250! I am taking 2mg twice a day. My doctor says all is OK.
Avatar f tn He takes 2 tablets Glycomet Trio 1 (Metformin HCL Sustained Release, Glimepiride & Voglibose Tablets) - 1 before taking lunch and before taking dinner.
Avatar n tn After this happened a couple of times I quit taking the Metformin. About a year later I was then diagnosed with T2 and am now on Glimepiride and have since began having these episodes again. They begin in the jaw area primarily the glands just below my jaws, with a sting/tingling that intensifies and radiates out all around my ears, neck throat and surface of my chest, and my upper torso goes ice cold. This takes place any where from a 30 second to a 3 minute cycle.
Icecream The main concern I would have about the addition to Lantus 20 units daily would be the risk of low blood sugar, especially in combination with glimepiride. Both Lantus and glimepiride can cause low blood sugar or hypoglycemia. Just make sure you're watching for the signs of low blood sugar, which are, sudden headache, feeling shaky, and weakness. There are many more signs of hypoglycemia and I encourage you to research it more yourself.
Avatar m tn Please do not put off calling your doc today. I looked up Amaryl (glimepiride) and it is used by type 2 diabetics to lower glucose levels. There's a discussion going on in this forum about type 2, after long periods of time (how long is unk), reversing into type 1 diabetics. In your case it seems you are combating low glucose levels and may have a flipped 180ยบ. Let us know what your docs says. You will help a lot of readers by posting your history if you did turn into a type 1.
Avatar n tn s ability to readily detoxify the reactive intermediates or easily repair the resulting damage. Disturbance in this normal redox state can cause toxic effects through the production of peroxides and free radicals that damage all components of cells, including protiens, lipids and DNA. Uric Acid is increased by diet of high fructose intake (corn syrup) and purines found in high amounts or animal food products. Check your diets, my husband drank alot of Mountain Dew and likes to hunt.
Avatar n tn How are you doing with monitoring your diet? Do you get regular exercise and drink plenty of water? Sometimes the medications that are helpful and keep things under control for a while, stop working or just need adjusted.
Avatar n tn Clonidine, Glimepiride, Byetta, Metformin, Amlodipine, Crestor, and Losartan HCT. Is it possible that it could be these meds? Please help!! I'm working by tail off and still have a GUT. Thank you in advance.
Avatar n tn I currently take glimepiride 4mg twice daily and actos 15mg once daily. What is the sucess of these two meds. I continue to have high blood sugar levels.
Avatar n tn Hi Doctor, My wife has consulted the doctor as advised by you and he has prescribed Cetapin 1000 mg 1-0-1 (metformin) along with Glimy-4(Glimepiride)1-0-0-. Hope this is OK.
1260255 tn?1288654564 s ability to make energy is reduced or stopped, and metabolic intermediates and toxic by-products begin to build up. The energy shortage in the tissues is the major cause of muscle weakness, fatigue and problems in the heart, kidneys, eyes and endocrine system. The buildup Of toxic intermediates can be responsible for liver problems, muscle cramps, brain dysfunction or even greater mitochondrial damage. Many times these two types of problems reinforce one another, each making the other worse.
1273125 tn?1365077526 Hey Scrappy - has your doctor suggested adding GLIMEPIRIDE to your Metformin? I am type 2, have been for 10 years - also only have 1/2 a Pancreas, as I had to have the other half removed due to a tumor in the head of my Pancreas - 8 hour surgery, and 8 days in the hospital, which is where the Insulin shots started. Initially, I came home from the hospital on both types of Insulin.
538277 tn?1214680105 He has put me on Carvedilol 25mg 2x a day, Nifedipine (Procardia XL) 60mg 1x day, Glimepiride 4mg 1x day, and continued me on Phenytoin EX 300mg @ night (had 3 seizures in 20yrs -age 24, 34, & 46)& Ecotrin 325mg 1 @ night. Have major problems with diaherra, and diverticular disease. Hospitalized in May of '07 w/preferations starting - there for 3 days, back in ER 1 wk, no insurance - kept me on antibotics for about 2 months. Alegeric to pencillin, tetracycline, & opiates.
Avatar n tn Thanks JB. to mike1105: thanks. You say it's a bit tricky to get the "intermediates" right. Since posting I located an old friend out of town(who is a D.D. but no longer practicing) and he told me over the phone several things: 1) he never heard of "intermediates" for the type of denture replacement I described. I had a functioning set of dentures which were there to be used for control prior to the surgery - they were not.
Avatar m tn It is probable that these cells could support viral replication because hepatitis B virus DNA replicative intermediates, viral transcripts and HBsAg and HBcAg proteins were detected in most. These findings may be relevant to the initiation of extrahepatic syndromes associated with chronic hepatitis B virus infection such as vasculitis, glomerulonephropathy, neuropathy and dermatitis.
Avatar m tn Similarly, extensive analyses of intrahepatic woodchuck hepatitis virus (WHV) and duck hepatitis B virus (DHBV) DNA intermediates under nucleoside analog therapy clearly demonstrated that cccDNA become the predominant form of viral DNA replication intermediates upon long-term suppression of viral DNA replication40 and 41. These findings strongly suggest that cccDNA is the most stable HBV replication intermediate and elimination of cccDNA is the key to cure HBV infection.
Avatar n tn I went to an endocrinologist who put me on Vicotza and glimepiride. M numbers have dropped drastically. I am never over 150 now. Have been on it for maybe a month. So insulin is an option but there are other medications that help too. Problem with insulin is it cause weight gain which can perpetuate the over -weight high blood sugar issues! Vicotza can work as a weight loss aide as well. Call an endo soon!!
Avatar m tn Alan McLachlan at the University of Illinois-Chicago, dramatic reductions in viral transcripts, viral replicative DNA intermediates, and intracellular HBV core antigen were observed in the liver after two weekly doses.
Avatar m tn Nicotinamide suppressed both HBV DNA replicative intermediates and 3.5-kb mRNA expression. Moreover, nicotinamide treatment also suppressed core protein expression and the secretion of the hepatitis B surface antigen (HBsAg) and the hepatitis B e antigen (HBeAg) in HBV-expressing cell models. Importantly, nicotinamide treatment suppressed serum HBV DNA, HBsAg and HBeAg levels and liver HBV DNA in HBV-transgenic mice.
Avatar n tn I then told him my little experiment and asked if we could switch to something else. We are experimenting with just Glimepiride 2 mg for two weeks to see how I do. My last 3 A1C were 6.5,6.3 and 6.2. I was able to exercise for 20 minutes on the stationary bike this morning for the first time in a year without my legs feeling like they were going to fail me. Thanks again, rmworrywart.
Avatar n tn This was preprandial I test twice a day and I have been on metaformin and glimepiride for two years. I walk 3 miles a day or more.I do not ignore my diet. I have a a bad cold . Thanks for the lecture tho what I .
Avatar m tn The siRNAs in ARC-520 intervene at the point of DNA transcription, upstream of where nucleotide and nucleoside analogues act, and can deeply knockdown all HBV gene products, including proteins and the viral intermediates necessary to produce viral DNA.
Avatar f tn Similarly, there is no risk from his putting his fingers in your mouth. STDs are not transmitted through by hands as intermediates. In answer to your specific questions: 1. No, no risk. 2. No - hand to genital transmission is very inefficient and not a realistic concern. 3. No, not unless it leads to penetrative sex (which it often does, no matter what was "planned". 4. Very briefly if at all. 5. No need for testing Hope this helps.