Glimepiride bioavailability

Common Questions and Answers about Glimepiride bioavailability

amaryl

1068689 tn?1325827206 My new doctor changed my prescriptions from regular Met to Met XR and added 2mg of Glimepiride. My BG's have been above 300 for last few months and nothing seems to get them down. Doc thinks this change should do it. I've only taken it twice now but since taking it I've been dizzy. Quite enough I need to lay down. I know it says this may be a side affect but does it go away? It brought my BG's down as I said from over 300 3 hrs after eating to 180 just now.
Avatar n tn Atorvastatin is supposed to be one of the two most effective statins in lowing cholesterol so you are on a good one. Bioavailability is how well a med is absorbed and used by the body and bioavailability varies among the statins. It's actually a desired thing. The liver is the target organ so if it is slowed down in the liver (where this happens), it's in the target organ. But honestly, that is hard for me to understand.
Avatar m tn the drug glimepiride, is not making my blood sugar level lower; instead is higher 250! I am taking 2mg twice a day. My doctor says all is OK.
Avatar f tn He takes 2 tablets Glycomet Trio 1 (Metformin HCL Sustained Release, Glimepiride & Voglibose Tablets) - 1 before taking lunch and before taking dinner.
Avatar n tn After this happened a couple of times I quit taking the Metformin. About a year later I was then diagnosed with T2 and am now on Glimepiride and have since began having these episodes again. They begin in the jaw area primarily the glands just below my jaws, with a sting/tingling that intensifies and radiates out all around my ears, neck throat and surface of my chest, and my upper torso goes ice cold. This takes place any where from a 30 second to a 3 minute cycle.
Icecream The main concern I would have about the addition to Lantus 20 units daily would be the risk of low blood sugar, especially in combination with glimepiride. Both Lantus and glimepiride can cause low blood sugar or hypoglycemia. Just make sure you're watching for the signs of low blood sugar, which are, sudden headache, feeling shaky, and weakness. There are many more signs of hypoglycemia and I encourage you to research it more yourself.
Avatar m tn Please do not put off calling your doc today. I looked up Amaryl (glimepiride) and it is used by type 2 diabetics to lower glucose levels. There's a discussion going on in this forum about type 2, after long periods of time (how long is unk), reversing into type 1 diabetics. In your case it seems you are combating low glucose levels and may have a flipped 180ยบ. Let us know what your docs says. You will help a lot of readers by posting your history if you did turn into a type 1.
Avatar m tn Although a standard meal did not affect ribavirin bioavailability (F1), administration of ribavirin with a high-fat meal increased bioavailability by 46% relative to the fasting state. A high-fat meal prolonged the duration of the zero-order input part of the absorption model, with D1 increasing from 0.498 h (fasting and standard meal) to 0.740 h. The type of meal also influenced the first-order input part of the absorption model (Table 1).
Avatar f tn When a medication is administered intravenously, its bioavailability is 100%. However, when a medication is administered orally, its bioavailability decreases because not all of it is absorbed. So 70% bioavailability means that, from the dose you took, 70% of it reached systemic circulation. "Two studies have been carried out to assess the effect of food (ie, a high-fat breakfast) on the bioavailability of a SINGLE oral dose of ribavirin. An initial study by ICN Pharmaceuticals, Inc.
Avatar f tn Also as a side note, Opana oral bioavailability is actually very low. Lower than morphine I believe the bioavailability is around 10 percent. However, if you reach your optimal dose, bioavailability matters little. I see that this post is from October 2011. But since I have this typed, I'll post anyway :) Good luck and gentle hugs.
Avatar n tn How are you doing with monitoring your diet? Do you get regular exercise and drink plenty of water? Sometimes the medications that are helpful and keep things under control for a while, stop working or just need adjusted.
Avatar n tn Clonidine, Glimepiride, Byetta, Metformin, Amlodipine, Crestor, and Losartan HCT. Is it possible that it could be these meds? Please help!! I'm working by tail off and still have a GUT. Thank you in advance.
Avatar n tn I currently take glimepiride 4mg twice daily and actos 15mg once daily. What is the sucess of these two meds. I continue to have high blood sugar levels.
Avatar n tn Hi Doctor, My wife has consulted the doctor as advised by you and he has prescribed Cetapin 1000 mg 1-0-1 (metformin) along with Glimy-4(Glimepiride)1-0-0-. Hope this is OK.
1654177 tn?1319838494 Also best not to take drugs with lots of fiber as they can bind to the fiber and pass through the system before total absorption thus decreasing bioavailability. You need all the bioavailability you can get!.
Avatar f tn Blood tests are not accurate for testing the active bioavailability of sex hormones in the cells and tissues. They only test what's in the blood stream. They aren't accurate for testing when a patient is using bioidentical topical creams. I've had two holistic doctors tell me this and have read numerous articles about which testing is correct depending on which type of hormones you're taking.
Avatar n tn The ascorbate in Ferrous Ascorbate helps retardation or prevention of Fe(II) oxidation by ascorbate and to the existence of Fe(II) as a chelate with ascorbate ( vitamin C if you like ). Ferrous Ascrorbate will have a better bioavailability but you can add a vitamin C and vitamins B complex with sodium feredetate and have pretty good results. Depending on your needs; are you lacking iron? anemia?
1431734 tn?1421011671 The component of the final population pharmacokinetic model that describes the absorption phase is complex. Although a standard meal did not affect ribavirin bioavailability (F1), administration of ribavirin with a high-fat meal increased bioavailability by 46% relative to the fasting state. A high-fat meal prolonged the duration of the zero-order input part of the absorption model, with D1 increasing from 0.498 h (fasting and standard meal) to 0.740 h.
1273125 tn?1365077526 Hey Scrappy - has your doctor suggested adding GLIMEPIRIDE to your Metformin? I am type 2, have been for 10 years - also only have 1/2 a Pancreas, as I had to have the other half removed due to a tumor in the head of my Pancreas - 8 hour surgery, and 8 days in the hospital, which is where the Insulin shots started. Initially, I came home from the hospital on both types of Insulin.
538277 tn?1214680105 He has put me on Carvedilol 25mg 2x a day, Nifedipine (Procardia XL) 60mg 1x day, Glimepiride 4mg 1x day, and continued me on Phenytoin EX 300mg @ night (had 3 seizures in 20yrs -age 24, 34, & 46)& Ecotrin 325mg 1 @ night. Have major problems with diaherra, and diverticular disease. Hospitalized in May of '07 w/preferations starting - there for 3 days, back in ER 1 wk, no insurance - kept me on antibotics for about 2 months. Alegeric to pencillin, tetracycline, & opiates.
Avatar f tn The component of the final population pharmacokinetic model that describes the absorption phase is complex. Although a standard meal did not affect ribavirin bioavailability (F1), administration of ribavirin with a high-fat meal increased bioavailability by 46% relative to the fasting state. A high-fat meal prolonged the duration of the zero-order input part of the absorption model, with D1 increasing from 0.498 h (fasting and standard meal) to 0.740 h.
Dinosaur Thank you for your question, Yes, it is recommended you take it in the morning on an empty stomach, at least 30 minutes before food. Taking levothyroxine with food may cause reduced bioavailability and may lower drug levels leading to signs or symptoms of hypothyroidism. In addition, cottonseed meal, walnuts, and dietary fiber may decrease absorption of levothyroxine from the GI tract.