Gleevec test

Common Questions and Answers about Gleevec test

gleevec

Avatar n tn I was diagnosed with CML and given Gleevec 400 ml. After taking gleevec for 2 weeks doctor took additional blood test. My WBC dropped from 36.5 to 7.1 and all other blood counts came down to normal range. I'm wondering if gleevec could give such fast hematological response or I was possibly misdiagnosed originally. I don't and didn't have any symptoms, my spleen and liver weren't enlarged, no enlarged lymph. Should I get second opinion asap? Please, help me.
Avatar n tn After two weeks on 400mlg gleevec my WBC droped from 36.5 to 7.1. My doctor told to come for additional test in two weeks. Now my WBC is 1.3 and absolute neutrophils count is 0.04. I was told to stay home on antibiotics. How long it may take for my counts to clime back to safe range. And of course, I'm off gleevec right now. Does it seem that dose of 400mlg is too high for me.
Avatar m tn Hi, I don't know the answer -- but since both CML and Gleevec toxicity produce anemia because of marrow suppression, maybe it's not possible to tell the difference. E.g., both would show a low reticulocyte count. This full text paper on anemia from Gleevec https://onlinelibrary.wiley.com/doi/full/10.1002/ajh.23879 shows that other signs such as red blood cell size can vary, so that doesn't seem to help. Sorry.
Avatar n tn Is it possible that after taking gleevec for only two weeks WBC droped from 36.7 to 7? All other blood counts are also came back to normal range. Could doctor make mistake in diagnosis of CML? Maybe I should get seg second opinion?
Avatar n tn Am on Gleevec 400mg, now having problems with blisters on the palm. What can I do about it?
Avatar f tn I was diagnosed last year and was immediatley put on gleevec 400mg/day.At my last consult my metabolic stats had risen,hence blood tests to determine if the gleevec is no longer working.I am still in firstphase and wonder what my options are if the gleevec is no longer an option.Amin pretty good form,just very tired and a lot of bone pain.
Avatar m tn I have CML and was treated with Gleevec for 4 years and achieved remission. I have for the past several months been experiencing sudden onset of weakness which last for hours, to days. My blood pressure which has remained under control for several years with atenolol has been running 145/105 and higher for the past three to four months. I have a feeling of fullness in my stomach, and I have sporatic episodes of mild coughing, this occurs maybe once a week.
Avatar f tn i was diagnosed with cml in march of 2009 and was also taking 150mg of elavil at bedtime to control migraines for like 10 years. then this past dec. a heart test showed i had prolonged qt of the heart so i was stopped 'cold turkey' by a dr and its been down hill ever since. i have had the shakes, loss of appetite and constant nausea. i wake up evey morning shaky really bad.
Avatar n tn You might find he starts to be able to tolerate the pill. Gleevec is first choice for treating CML, and if he is doing good in every other way then encourage him that he is doing great. I hope this helps you. I would be glad to help you with any other questions.
225036 tn?1294509400 I wish I could have seen that episode. Gleevec (discovered by Dr. Druker - a real cutie pie with lots of energy, works here in town) seems so promising. But like all medications, they take years to test it and test it before it's really out there. He's been working on this for years but I don't know how many. I do hope it works just as well on other forms of cancer.
Avatar f tn A definite diagnosis of chronic myelogenous leukemia (CML) is made by demonstrating the existence of the Philadelphia chromosome on cytogenetic studies of the bone marrow cells (harvested by bone marrow biopsy) or by detecting the bcr-abl gene (this is the defective gene responsible for the CML) by means of a test called polymerase chain reaction or PCR. If these two tests were not done, I can't see how a diagnosis of CML can be made.
Avatar m tn I should mention that I have CML but it has been in remission for the last two years and I am no longer taking Gleevec. I am scheduled to be looked at by a group that kills the nerve endings in the heart that causes AF but there is an 18 month waiting period. My question is how many times can I be cardioverted and what is the downside of having it so often?
Avatar n tn * buprenorphine Metabolized into norbuprenorphine by cytochrome-P450 isoenzyme 3A4 * Tyrosine kinase inhibitors, including Gleevec and Tasigna, used to treat chronic myelogenous leukemia and gastrointestinal tumors.
Avatar f tn If you are particularly interested in determining whether your son also has an autism spectrum disorder than a qualified profressional who can administer a test such as the ADOS (Autism Diagnostic Observation Schedule) can provide this service for you. In some cases having this diagnosis may make more resources available to you. Some of the behaviors you describe (persistent interests in trains/WWII, hand flapping, social awkwardness) also occur frequently in persons with autism.
148588 tn?1465778809 “The fields of gene therapies, viral delivery, and other personalized therapies are progressing rapidly,” Church says, “with several clinical trials succeeding into Phase 2 and 3,” when the therapies are tried on progressively larger numbers of test subjects. “Many of these treatments target cells that differ in only one—rare—genetic variation relative to surrounding cells or individuals.
Avatar m tn term=cmml I see different drugs in the pipeline, including Gleevec which is very successful in other blood cancers. I do see some monoclonal antibodies there. Aha, the bortezomib study is here: http://clinicaltrials.gov/ct2/show/NCT00437086 But it was just a pilot, i.e., the very earliest stage of investigation. But that apparently showed it to be safe, as expected. IOW, it is not a risky last-chance drug. Neither most likely are none the MABs risky, they are very mild in side effects.
Avatar f tn She is taking Gleevec for chronic myelogenous leukemia, which has been "controlled" completely for about 3 years. I mention this in case it bears on the situation.
Avatar f tn Could you please review pulmonary test results and tell me your impressions?
804317 tn?1274207759 I am planing to take another test in two weeks. The person at the free clinic explained that I have to take the rapid HIV test three times in order to be sure of the result. This is very worrying to me because my test on April 20 could count for nothing. Again, How accurate is the rapid test at 70 days, and is there a better test to take?
Avatar m tn Move along.