Gleevec for cml

Common Questions and Answers about Gleevec for cml

gleevec

Avatar n tn Is it possible that after taking gleevec for only two weeks WBC droped from 36.7 to 7? All other blood counts are also came back to normal range. Could doctor make mistake in diagnosis of CML? Maybe I should get seg second opinion?
Avatar m tn Hi, I don't know the answer -- but since both CML and Gleevec toxicity produce anemia because of marrow suppression, maybe it's not possible to tell the difference. E.g., both would show a low reticulocyte count. This full text paper on anemia from Gleevec https://onlinelibrary.wiley.com/doi/full/10.1002/ajh.23879 shows that other signs such as red blood cell size can vary, so that doesn't seem to help. Sorry.
Avatar n tn I was diagnosed with CML and given Gleevec 400 ml. After taking gleevec for 2 weeks doctor took additional blood test. My WBC dropped from 36.5 to 7.1 and all other blood counts came down to normal range. I'm wondering if gleevec could give such fast hematological response or I was possibly misdiagnosed originally. I don't and didn't have any symptoms, my spleen and liver weren't enlarged, no enlarged lymph. Should I get second opinion asap? Please, help me.
Avatar f tn Fortunately, in the last several years, two other agents (these are referred to as second-generation tyrosine kinase inhibitors) – dasatinib (Sprycel®) and nilotinib (Tasigna©) have both been shown to be at least equally effective (and likely better) in treating CML. They have different side effects, but either can be used as initial therapy for CML or after imatinib therapy. This may be helpful to you: http://www.medhelp.
Avatar m tn I have CML and was treated with Gleevec for 4 years and achieved remission. I have for the past several months been experiencing sudden onset of weakness which last for hours, to days. My blood pressure which has remained under control for several years with atenolol has been running 145/105 and higher for the past three to four months. I have a feeling of fullness in my stomach, and I have sporatic episodes of mild coughing, this occurs maybe once a week.
1004138 tn?1316251113 No there is no herbal treatment for CML!!! Were you diagnosed with CML, and if so are you seeing a specialist and what treatment are you on.? I am being treated for CML, and was told not to even drink herbal teas well on my medication. Share some more information so I can help you. I have had CML for 13 years.
Avatar f tn Hi there. It is important to be empathic, and let your brother know that you are always there for him. However, you should not overdo this, since this might lower your brother's self esteem further and cause him to have self-pity. CML is a manageable disease given the appropriate medications. Not all CML's are candidate for Gleevec. Only those who tested positive for the philadelphia chromosome or the bcr-abl gene would be candidates to receive gleevec.
Avatar n tn You might find he starts to be able to tolerate the pill. Gleevec is first choice for treating CML, and if he is doing good in every other way then encourage him that he is doing great. I hope this helps you. I would be glad to help you with any other questions.
Avatar f tn There is no genetic basis for the CML therefore she was not put on Gleevec. She is on Hydrea to keep the wbc count down to a more normal level. I think the only thing that led to the CML diagnosis was the extremely high wbc with no sign of infection or other cancer. Mayo did the same blood tests as the hometown doctor, as well as the lab in Iowa City. I would like them to run other tests but havent a clue what to ask for.
Avatar f tn i was diagnosed with cml in march of 2009 and was also taking 150mg of elavil at bedtime to control migraines for like 10 years. then this past dec. a heart test showed i had prolonged qt of the heart so i was stopped 'cold turkey' by a dr and its been down hill ever since. i have had the shakes, loss of appetite and constant nausea. i wake up evey morning shaky really bad.
Avatar n tn I am a Leukemia Survivor also. What type of Leukemia did you have, and what was your treatment. I have CML, and have achieved a major molecular response through a oral chemo drug called Gleevec. It does not sound like these patches have anything to do with the Leukemia. I would see a Dermatologist to have them evaluated. I hope that helps you a little bit.
Avatar f tn My mum has been taking Glivec for close to 20 years for her leukemia. Recently, she has been in and out of hospital for critically low sodium level. This has occurred for about a year. Anyone experienced similar problems or know of any research showing causal link?
Avatar m tn I should mention that I have CML but it has been in remission for the last two years and I am no longer taking Gleevec. I am scheduled to be looked at by a group that kills the nerve endings in the heart that causes AF but there is an 18 month waiting period. My question is how many times can I be cardioverted and what is the downside of having it so often?
Avatar n tn Hi. Response to imatinib (gleevec) can be dramatic just like what you experienced. Myelosuppression with neutropenia (decrease in neutrophils) and thrombocytopenia (decrease in platelet count) can be a side effect of treatment. Usually, discontinuation of drug intake is advised until the blood counts increase. You should have your white blood cell count repeated after 1-2 weeks and see if it already improves. You should report to your doctor if you experience any symptoms like fever.
Avatar n tn Am on Gleevec 400mg, now having problems with blisters on the palm. What can I do about it?
Avatar f tn Hi, what you need to do is get a copy of that test which may talk about finding the Phila Chromosome. Maybe it's even online? If it does say that, then the next step would be to find out the odds of a false positive. The word "suspicious" stands out in your account, being far from "conclusive". On such an odd circumstance, I'd even wonder about a lab mixup or error. A WBC of 18 is not necessarily a sign of a blood cancer.
Avatar n tn My 24 year cousin is my best friend and was just diagnosed with CML and her doctors are very optimistic, but she has so many qiestions she is scared to ask. They are going to put her on the "Miracle Pill" will she lose her hair? Will is hurt her chances of have children? As optimistic as the doctors are, is there any chance that this is a fatal condition? We are scared should we be?
Avatar m tn I went to the doctor for an infection and said I had been short of breath for about 3 weeks. Turns out my heart rate was dropping into the low 40's upper 30's. Well as they monitored that and did blood work they also found the CML. Is this a common thing to have low heart rate with CML? As a coworkers friends daughter was also just diagnosed with the CML she too is having low heart rate issues. Sound like too much to be coincidence.
Avatar n tn My bf has CML and he had a partner who has HIV my question is can HIV be transmitted to him as he is already a CML patient ? My second question if he has both CML and HIV but the HIV is inactive what are the probability of me getting infected with HIV?
Avatar f tn Of course I will keep Reese in my prayers, of course! I went back to read your earlier posts. It looks like Reese is young with a lot of energy. Do you have any idea what happened? Please, if he isn't feeling well enough to eat by tomorrow, he should see the vet. If it's not serious now, it can become serious quickly when our kitties stop eating. Keep us updated, okay?
Avatar f tn Yes, CBC tests can come back fine even with cancer present (usually in the early stages), but my guess is your daughter most likely has an infection brewing, causing the elevated leukocytes and mouth sores. This is usually the reason for elevated wbc's. Family history of CML is not a risk factor, as it a chromosomal mutation that is acquired after birth (and usually in older people).
Avatar f tn I'm so sorry this is happening to your husband. Your husband was on therapy for his CML. A target high dose therapy. Apparently, he had adverse effect of some kind during the therapy. Transfusions can be a part of having leukemia and he does have a two blood related diseases. Also, there are problems related to transfusions themselves. There are many variables and they just might not know exactly which one is causing the problem.
Avatar m tn I regularly dont drink very much but one weekend (about 2 weeks ago) i got together with some friends and we partied for like 4 days. On the second night i vomited and for the next couple days i had little to no food .On the third night i only had 1 or 2 beers and the last night i didnt drink at all. Its been almost 2 weeks and ever since that weekend ive felt really out of it and light headed but recently it seems have gotten a little worse. im 16, about 6 feet tall and weigh 145.