Fluoxetine and tamoxifen
Common Questions and Answers about Fluoxetine and tamoxifen
prozac
ll see new warnings not to combine tamoxifen with certain SSRIs..paroxetine, fluoxetine, and sertraline. .... Women have a higher risk of breast cancer recurrence if they take tamoxifen along with paroxetine, fluoxetine, or sertraline... but NOT citalopram, escitalopram, or fluvoxamine. .....About 30% of women on tamoxifen also take an SSRI for depression or hot flashes. FDA will add new warnings..
What about if only uterus has been removed and the overies are still there! Can she still take Tamoxifen ??
Because of drug interactions, caution is recommended when tamoxifen and CYP2D6 inhibitors (e.g., paroxetine, fluoxetine, bupropion) are used concomitantly.
When advising women about adjuvant therapy, clinicians should consider the adverse effect profiles of tamoxifen (venous thromboembolism and endometrial cancer, polyps, and hyperplasia) and AIs (osteoporosis, fractures, and arthralgias).
I have been on Tamoxifen for a little over two years for breast cancer. I am 46 and pre-menopausal. The first 22 months on the tamoxifen I had my period and occassional hot flashes. then one month my period stopped and my hot flashes. At month 27 on Tamoxifen, I had an ultrasound that shows a lickening of the uterean wall and 3 complex ovarian cysts. My Dr. is doing a biopsy but my question is why would my periods AND the hot flashes go away completely?
Hi, I am a 27 year old woman who was diagnosed with breast cancer at age 25, I had a complete mastectomy and given the option of chemo or tamoxifen, we picked tamoxifen becasue being able to have children is very important to us. I have been taking this for just over one year and I had MANY side effects to tamoxifen, so much so that I have considered stopping it.
After surgery, I had radiation therapy, plus taking tamoxifen. My cancer is stage 1 and grade 1Gradually, my hot flash is stopped and my life is back to near normal. I noticed that I always very thirsty, my eyes are dry, my skin, hair also dry. I also have joint pain occurred in joint, both small and large joint. I read the symtom of Sjogren's syndrome which is a incurable auto-immune system problem which is that the glands produce lubrication has stop function properly.
Just to add to what Lauren said regarding tamoxifen vs. other AI's, they do work differently in the body. Tamoxifen works by blocking the body's use of estrogen, whereas AI's reduce the amount of estrogen present in the body. In studies of breast cancer patients, AI's have proven to work better than tamoxifen in preventing recurrence, and there are far fewer serious side effects with AI's than with tamoxifen, too. Tamoxifen can cause blood clots, and stroke..
Yes I suffer from the same problems as you describe above and have been on and off fluoxetine for several years for major depression and I can reassure you that the side effects as far as increased anxiety at the beginning of treatment are common and I have had to take an antianxiety medication for the first couple of weeks to combat this effect. In 2-3 weeks it should subside and that's usually when I also start to feel the desired effect of fluoxetine.
went if ever can i expect my pain to go away, since going through chemo and starting tamoxifen, i've been having bad pain and stiffness in hands and feet. medication vicodin help some, also some stiffiness in knees. my doctor has no answers and keep try different medications that is not working. please have some anwers for me . pain started after taking tamoxifen in april, stopped chemo in march. what can i do or take to relief the pain. thank you.
I am aware that provera is contraindicated in case of hormone-driven breast cancer, but was wondering whether the fact that I am taking tamoxifen as prevention and the fact that provera is given for four months make any difference?
I am also wondering if I will have to choose between what cancer to try and prevent, that of the womb or that of the (other) breast?
I am 36 and at the moment do not consider hysterectomy an option.
Thanks,
Robin
Thank you.
I have been on tamoxifen for 5 weeks now after completing chemo and in the process of completing radiotherapy for breast cancer. I developed bilateral pulmonary embolisms a few days ago due to a dvt in my thigh which i was unaware of. I am on clexane injections for the next 6 months. Is it safe to continue on the tamoxifen? Is there an alternative to this medication that does not have such serious side effects.
I was 39 when diagnoised last year and had 4 cycles of AC chemo, followed by radiotherapy and now Tamoxifen for 5 years.
I continued to have a period during chemo, but at the end of my chemo, the blood test showed I was in menopause status, but could not tell if it was permanent of not. 2 months later I did another blood test and was back ovulating. My periods continued and even now that I am on tamoxifen.
not sure what this means.. melatonin reduces the antidepressant effect of fluoxetine.. and then in the last sentence fluoxetine has lead to a measurable depletion of melatonin in people..
Fluoxetine (Prozac) has the slowest elimination of the SSRIs.
Hi,
I too was taking Tamoxifen and then was switched to Arimidex and then Aromasen. I am now back on Tamoxifen. I had so many problems with the other meds. I am very sensative to meds and the later 2 did not work. I have a few problems with Tamoxifen but it is better than the others for me.
My Dr. said that it is not a problem being in "forced" menopause and the fact that I had a hysterectomy as well.
One thing we always have to remember is that we are our own advocate...
re doctor will take all the facts of your specific medical history and current condition into consideration. In fact, I have LCIS and Tamoxifen is usually prescribed for that, but my oncologist and I decided it wouldn't be right for me. You would just need to be sure the doctor has all the information needed including the name of your other doctor/s, so they can consult and share your medical history.
My brother went to a psychiatrist and he prescribed him fluoxetine and xanax. He said that my brother should take one 20mg tablet of fluoxetine for the morning and 0.5 tablet for xanax for morning and night for 14 days . He said to take the 0.5 mg xanax tablet half in morning and the other half at night
So, my brother took the fluoxetine and xanax for 14 days and then again went to the psychiatrist. My brother has not felt any improvement for his ocd or depression from the tablets.
Concomitant use of tramadol and serotonin reuptake inhibitors (SSRIs) such as fluoxetine increases the risk of seizures and serotonin syndrome. It may also reduce the pain relieving properties of the tramadol. If you must take tramadol, do not take it at the same time as fluoxetine. Try to take tramadol and imitrex a few hours apart from the fluoxetine.
I am 38 years old and 4 and half months pregnant with my first baby. Before getting preg. I was taking 20 mg of fluoxetine once a day. When I first found out I was preg. i stopped. I recently experienced panic attacks and my doctor prescribed the same medication. Is it safe for my unborn child? I am very concerned please advise me!
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