Flexeril and liver

Common Questions and Answers about Flexeril and liver

flexeril

I have been taking two to three 10 mg tablets a day, to help me stay away from Norco, and the rest of the opioid family... and now I would like to stopt the flexeril... It is apparently much like the old tricyclic antidepressants imipramine and desipramine... so I wonder what kind of titration was used for them...?
For anyone interested in the low down on Acetaminophen and Your Liver. http://hcvadvocate.org/hepatitis/factsheets_pdf/Acetominophen.
I review some blood tests that I have had in the past and my ALT has usually been around the low 20's, as was the AST. None of my liver chemicals have ever been high (last test was in March 2007, ALT was 23). I am a 26 year old caucasion male with no known health conditions other than borderline high cholesterol (around 200-210) I eat moderately healthy. I work a sedentary job. I exercise 2-3 times per week.
Three months ago I had a cervical spine fusion, and was taking Ultracet and Flexeril before surgery and now only occasionally need Flexeril. Which of these medicines could contribute to the abnormal LFT? I drink a glass of wine each night, and maybe 3-4 glasses on a weekend night. Could the wine cause the liver abnormalities? My doctor wants me to quit taking the pravachol and retest in two months. Should I be concerned? Should I be panicked?
Now, I come to the question. I recently had presurgical testing and my liver enzymes have once again brought up concerns. My bilirubin is 1.3, ALPhos 172 AST 81 ALT 115 As you can surmise, I have had alot of medical treatments, and surgeries. I seriously don't think I can handle much more. Is there a chance I can just blow this off for awhile? I dont want anymore tests. It isnt the tests that bother me. It is the ambiguous results.
2 mg of Tylenol. Sometimes I would take my Flexeril with it as well and up to 2 (10 mg.) Valiums for added pain control and muscle spasms. Out of that week I may have added Ibprofen or extra Tylenol to supplement my other pain meds. Yes I was taking a lot of meds but the pain was unbearable and I was not functional without lots of pain meds. On the 3rd day of Lortan I probably went overboard and took 4 at one time (on an empty stomach because it works best) and I may of had 5 total that day.
2 mg of Tylenol. Sometimes I would take my Flexeril with it as well and up to 2 (10 mg.) Valiums for added pain control and muscle spasms. Out of that week I may have added Ibprofen or extra Tylenol to supplement my other pain meds. Yes I was taking a lot of meds but the pain was unbearable and I was not functional without lots of pain meds. On the 3rd day of Lortan I probably went overboard and took 4 at one time (on an empty stomach because it works best) and I may of had 5 total that day.
I ended up on the current solutions because of not wanting the oxycontin/morphine they offered me, nor the neurotin due to it's bad rap on the liver (and flat lining the brain according to 2 friends.) I've always read up (the last 30 yrs.) before taking anything and avoided anything that would hurt my liver, (like steroids etc.) Ironic then to end up with HCV. Any suggestions would be welcome.
The only muscle relaxers prescribed for me are Skelaxin(which is bad for the liver-but doesn't make you drowsy) and Valium. In my opinion, Valium is the safest & works well for short term use.
I wanted to post something on the topic as I am a Chronic Pain patient who has become pregnant. I'm currently in my 23rd week of the pregnancy and am having trouble finding a Pain Management Provider who will see a pregnant woman, or a high-risk OB who will treat Chronic Pain. I have been told that Maternal-Fetal Medicine Speicalists will provide pain relief for pregnant chronic pain patients, however I been told that mine will not.
In a recent physical exam, they found high cholesterol and did a test for one of the liver enzymes. They found it elevated and subsequent tests found all were elevated. I am to get a CT scan next week. Immediately before the symptoms developed, I was taking flexeril for about a week (for a pulled muscle). I seem to have had the classic symptoms of drug-induced hepatitis, except for Jaundicing and vomiting. I have discontinued all medications except benadryl.
In my heart, I swear I think Flexeril was hurting my Hep C liver and was one reason my enzymes shot up and my platelets, rbcs, and wbcs went down.
If u could answer about the roxycodone...
Did more bloodwork and liver enzymes were normal. My aunt tells me that my gallbladder may be swollen and pushing against my liver which may cause my liver to function irradically. Sometimes normal, sometimes less than normal. I go for a HIDA Scan in 2 weeks. Also a month before my abdominal pain, I was having severe back pain and taking muscle relaxers (flexeril) and Ibuprofen as an anti-inflammatory, also Darvocet. I tried Mobic instead of Ibuprofen and had alot of nausea and swelling.
Yesterday around 11a, I took a 5mg Flexeril and boy did it do wonders. After a brief nap, most of my pain greatly subsided. The following hours, about 10p, I did see an uptick in stiffness but nothing compared to the pain before the Flexeril. I know Flexeril has an unusually long half-life, about 18 hrs. I've been invited to a small get-together this evening and i'm wondering if Id be okay having a mix drink and/or a beer, or if I should refrain?
I am on plaquenil, methotrexate, folic acid (an absolute must if you are on mtx), relafen, darvocet and flexeril. It was only after I started the injections of MTX that I got some relief from the fatigue. The mtx pills were just too hard on me - more side effects. My perspective on the meds is that sometimes the benefits outweigh the risks. Before I went on MTX, I had a very low quality of life, with MTX it is dramatically improved.
30 at night getting my kids dressed and ready for school and got into a wreck and don't remember anythig except vaguely a field sobriety test and vaguely gong to jail. I was also taking chatnix and my first dose of provigil. The doc. says I shouldn't have gone to sleep taking the provigil. I have stopped both the chantix and the provigil but I am still on plaquenil 200mg twice a day, flexeril 10mg three times a day, St. John's Wort, and ibuprohen! What is wrong with me?
Yeah My girlfriend had complications after a hernia surgery and she was put on this stuff. She doesn't take or enjoy pills at all and the doctor was very careful with this stuff. She was on for a few weeks and then they slowly tapered her off because as stated above it can cause seizures if you abrubtly stop. it didn't even help her pain either but that is not really relevant. It doesn't seem like much is known about this stuff so i would be careful.
About 10 months ago, I started experiencing terrible muscle cramps in my right leg and toes on both feet. I have seen a neurologist and tests indicate that I have muscle damage in both legs. My legs are so weak, that it is hard to do much walking without getting absolutely exhausted. I have had elevated muscle enzymes for many months now, have been tested for various autoimmune diseases, but all tests come back negative. The doctors seem to be puzzled as to what is going on.
well, for certain NSAIDs and GERD don't go together.I have to take tramadol (ultram) for some the the liver pain, (and a back injury) but am keeping it minimal as it raises liver enymes, as do a lot of meds, regardless of what type, put additional tax on the liver. >>>>>>>"My emotions at times were quite raw and my temper at a flash point. I would cry at TV commercials and slam the phone down on people.
I have taken it before and it does seem to help . Last night, I could not sleep at all. Took a flexeril and finally got to sleep. Then my 9 year old was up "scared" for 2 hours. He is going through a scaredy cat stage. No rest for the weary. Now it is very early and my 1 year old is "off the chain". So begins another day in the life of a young geezer.LOL. My endo. said the best advice he could give me is to keep a very good relationship with my rheumatologist.
I am trying to stay positive, but this is far from the first time I have stopped the narcotics and I wonder if it ever will end. Just wanted you all to know how much help you've been and thanks for being there!
Don't feel like the flexeril is a big deal. It is non-narcotic and non-addicting. (EVERYTHING is addictive to some) ;) It will also pretty much get rid of RLS. Both you and Cincee seem to be doing well. One more day.......One more smile. It makes me happy to see you both be able to lean on each and get through this together. To me, that is what this forum is all about.....HEALING.
Now I am going cold turkey and all I have is some vitamins, and flexeril. The ortho doc put in Ultram for me. Should I take it. Will it help me with the w/ds. Bottom line - my reg. doc was not in. New doc wanted to be a **** and said no meds. Go cold turkey and deal with it. I asked if there were any non-narcotic meds to take (clonidine ect.), he said nope. Anybody have any Idea's. I need them. My wife understands how bad this is going to suck for me now.
I also suffer from from chrons and migraine's and take topamax and asacol and robinul and reglan. My doctor started me on clonazepam for 3 weeks to give my liver a rest form the lortab, but I already have been getting some side effects that scare me like moody ness, feely depressed and not feeling right. My pain is getting worse since I stopped taking the lortab ( which I only took 1 tablet(s) 3 times a day.
Opioid-induced hyperalgesia is a condition where the increased use of opiates, like Oxycontin and hydrocodone, heightens one's sensitivity to discomfort and reduces their tolerance for pain. Essentially, people will increase the amount of painkillers they are taking as their discomfort continues to escalate, but the added medication can actually make their pain worse.
140, positive HG-B27, degeneration in my sacro-iliac joints and S1/L5-T10/11 with an anterior herniation of the T7/T8 disk, chronically low hemocrit/hemoglobin, mildly elevated platelets, and elevated sed rates (if you need to know anymore blood test results, just respond and I'll give them to you.
So I dug up some more info that I wanna share ... in case you are dying of curiousity. Or need more info like I do. ---------------------------------------------------------------------------------------------------------------------------------------------------------- http***mb.rxlist.com/rxboard/ultram.pl?noframes;read=3179 not just for breakfast anymore Posted By: mkny Date: Friday, 21 October 2005, at 3:53 a.m.
Welcome to Part 6! Please make yourself at home!
your right on when you said that taking a opiate for chronic pain is not the same as addiction. Many of the symptoms can and are the same such as tolerance and dependence. Drug addicts and chronic pain patience Are as different as ketchup and mustard. Not much of a correlation but you get my drift.
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