Filgrastim neupogen side effects
Common Questions and Answers about Filgrastim neupogen side effects
neupogen
Docs invoke the use of Neupogen at at different levels. I found the use of Neup to be a non-event, no side effects. Others expereince bone pain and injection site soreness. It's much better to use Neupogen than to reduce the dose of the Peg. The stuff works quick, within a couple of days. If he needs it once, he'll probably need it on a continuing basis during treament.
You can discuss ‘Neupogen (filgrastim) with the doc; this is a GCSF drug that stimulates bone marrow production of white cells. It is generally initiated when absolute neutrofils reach .500 or that vicinity; some docs allow closer to .350, depending on occupation and other matters.
Right now, the low neutrophils can be remedied with filgrastim (Neupogen, Neulasta), but nothing is prescribed for low platelets (whites involved in clotting) except for reducing the interferon. There is a drug (eltrombopag) that stimulates platelet formation but the FDA has not approved it to go with the HCV treament drugs, so insurance may not cover it.
It is always better to use the rescue drugs instead of reducing the peginterferon or riba, especially if you have not cleared yet.
Are you saying your mother in law has Leukemia? Filgastin or Neupogen is used for that. I don't know of other uses for it. She can't get it in the Philippines? If you can get a prescription from her doctor perhaps you can get it from a pharmacy here. Have a talk with a pharmacist here at one of the stores like Rite Aid, CVS any of those and see if they allow that.
After tx was done and continuing the neupogen for an additional 3 weeks, the side effects became more obvious. I believe the Inf/Riba masked the sx making it difficult to separate. As much as I appreciate that neupogen allowed me to not require a dose reduction of interferon, I began to not look forward to the shots, shoving another drug into my body with unknown effects.
Interferon can cause a condition called ‘neutropenia’ or the suppression of white blood cells necessary to fight infection. In some countries, the drug Neupogen (filgrastim) is available to combat this, and to keep patients on full dose HCV meds.
Filgrastim and PEG-filgrastim are relatively expensive; and they might not be available in all areas.
What I want to do is look up these meds and make a document for him that is easier to read regarding side effects, etc. But, this is not possible until I find someone who knows how to spell these meds, and/or maybe knows something about their side effects personally.
Would someone out there please help me with this? I would be so very, very grateful, as my friend does not ever get on the internet and I don't want to bother him again today about "what were those meds again.
HI ALL,HOPING U CAN HELP ME OUT WITH WHERE TO FIND/BUY MEDS LIKE NEUPOGEN FOR LOW WBC,IV HAD LOTS OF TROUBLE WITH LOW WBC AND MY DOC SAID AUSTRALIA HAS NOT APPROVED IT.
IM AN AUSSIE AND HOPING SOME1 KNOWS OF WHERE TO GET THIS STUFF,OR ANYTHING THAT WILL HELP.IV HAD MY DOSE LOWERED AND IT SHATTERS ME COS MY CHANCES WOULD BE MUCH HIGHER WITH FULL DOSE OF INTERFERON.
I DONT CARE WHAT IT COSTS I JUST WANT TO BRING MY WBC UP COS IV HAD SO MANY INFECTIONS AND FLUES ETC.
Yes, Neulasta is the pegylated version of Neupogen. A polyethylene glycol molecule or (“PEG”) is added to enlarge the Filgrastim molecule (Neupogen), thereby extending its half-life and causing it to be removed more slowly from the body.
I don't know what the dosage requirements are for Neulasta but it is not taken as often as Neupogen.
Neulasta® (pegfilgrastim) or NEUPOGEN® (Filgrastim) may reduce your chance of getting an infection, but it does not prevent all infections. An infection can happen anytime your neutrophil counts are low. Look for signs of infection, such as fever, chills, rash, sore throat, diarrhea, or redness, swelling, or pain around a cut or sore. If you have any of these signs, contact your health care professional immediately.
http://www.neulasta.com/starting-chemo-with-neulasta/about-neulasta-neupogen.
Hi. I am on week 60/72, second round of treatment. I was really really sick after shot for first few months and then this resolved and became tolerable at least. I now find that I am having these same significant side effects later in tx. This didn't happen last round, but I went 48 then. Anyone else have this happen?
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