IC can also occur and usually does along side other
pelvic conditions, like Pelvic Floor Dysfunction,
Fibromyalgia, IBS and others. We do know that most IC
patients have an increase in Mast Cells and histamine, which is why many doctor's start their patients out on an antihistamine to help treat it. This is also a found in many autoimmune diseases.
The symptoms of IC can vary greatly between patients and even the same patient throughout the day.