Fibrous dysplasia of the bone in adults is a rare anomaly
of skeletal
development caused by a defect in differentiation
of osteoblasts. This condition is associated with bone pain, bone deformity, and an increased incidence of fracture. Involvement of the skull is associated with headache along with dysmorphic features. Until recently, the principal treatment has been resection or fracture repair, although the latter is often palliative at best.