fentanyl and buprenorphine

I did know about the actions and uses of buprenorphine and .... and the fact that Suboxone has the additional naloxone component to prevent injection abuse. I didn't know that Fentanyl could "knock bupe right off its pins." You're right, there must be more but I can't even find at you are saying about Fentanyl on line. I found this about buprenorphine: "These properties make buprenorphine an effective maintenance treatment for opioid-dependent patients.

Even if you did wait 24-48 hours, the problem is that your tolerance is much higher than the amount of opioid stimulation produced by Suboxone and buprenorphine. At the ceiling effect level, buprenorphine has the opioid effect of about 60 mg of oxycodone—much less than what you got from the oxycodone and fentanyl combined that you were taking. All is not lost. You MUST keep taking the Suboxone; over 4-6 days, your tolerance will come down and you will feel better.

Eagle is correct, Cathy-- buprenorphine, Suboxone, and Subutex are all essentially identical. Buprenorphine has been around for 30 years; it used to be sold under the brand 'temgesic' in liquid form before being made as Suboxone, which is easier to dose. Buprenorphine is used for pain, mostly in Europe-- a skin patch in the UK called 'buTrans' releases 5-20 micrograms of bupe per hour through the skin. Six years ago, in 2003, Suboxone became available in the US.

I've had a cranial MRI which didn't show anything and I'm still awaiting LP results for the MS. I've been checked for most things, not Lyme, because it is not active in this part of the UK (it's only in southern counties, not this far north). Just got to keep slogging on I suppose...

Hi julie1224, I'm so glad that your Doctor took the x-rays but I know that you are frustrated that they didn't find an answer to your problems. :( I don't have any information about a "new" patch that is similar to Vicodin that is out. I couldn't find anything when I googled it. You might call your Pharmacist and ask him/her about it as they are up-to-date on every new med that is coming out. Did your doctor tell you what the name of the "new" patch is?

I have had great sucess with the Fentanyl Patch. I have used it for about a year now and it gives me around the clock relief for 48-72 hrs. You may want to do some research on the Patch or chat with your Doctor about it. I also take Oxycodone for breakthrough. Give it some thought.

Thank you So very much for your help and PLEASE EXCUSE the Time to REPLY, i was MOVING to a Warmer location, back Down the volcano and into town... I have read and Read ALL kinds of info and the Suboxone seems to be given as a DETOX drug for people who have been ABUSING PX MEDS Whether their Own px or Buying them illegally... ("Valium from Thailand! Real Oxy's from NIGERIA!!

Getting it cleared from your body will depend on your percentage of body fat, your metabolic rate, and the ability of your liver to break down the fentanyl. I would imagine that fentanyl could be found in your body for a month or so after stopping it, but the last couple weeks it would be in very low concentrations-- too low to measure by the standard urine tests out there, and too low to have much of an affect on you. OK... hallmark of addiction...

I just googled this, and found that there has been experimentation of giving fentanyl as a patch to cats, I assume they know exactly the dose and they were clearly doing it under lab conditions. But fentanyl can easily kill people, they think they are taking a little pill but it has a huge dose, and they die. Someone trying to guess and put together a dose for their cat at home is taking a huge risk. If a vet recommends a pain killer for a cat, he or she will be able to advise on the dosing.

ve read on holistic info sites that BUPRENORPHINE is the best and SAFEST pain med for cats....I know thats the one my Vet uses too. Is this for long term use?

For the past year I have been taking 75 mcg fentanyl patches every three days.I need and want to stop and get back to living a clean FUN life.I don't get them by prescription so I can not goto a dr to taper off.I have tried on my own and it was total HELL! The thought of those feelings again scares me to death.I read about Suboxone and wonder if someone here can tell me how it worked for them.Also money wise how much did it run?

Both Subutex and Suboxone are sublingual tablets, meaning you put them under your tongue to dissolve. Subutex is strictly buprenorphine hydrochloride. You begin treatment with this, and then when you are ready to move into the maintenance phase of the treatment, you switch to Suboxone, which is buprenorphine hydrochloride and naloxone, which guards against the meds being misused to get a high from them.

buprenorphine has a potency akin to that of fentanyl. A dose of 5-10 MICROGRAMS is a potent analgesic. A quarter of one tablet of Suboxone contains 2 mg of buprenorphine, or 2000 MICROGRAMS!! So any dose of Suboxone is 'overkill'-- even a sliver of a tablet contains an amount of buprenorphine that is quite high, and possibly over the 'ceiling dose'. Stopping 16 mg Suboxone is like abruptly stopping 30 mg of methadone...

Some opiates cause histamine release-- particularly morphine-- that can cause itching and a rash. Some high-potency synthetic opiates--namely fentanyl and sufentanil-- cause facial itching, particularly around and inside the nose. Some medications can cause a feeling of extreme restless called 'akathesia' that sometimes presents as intense itchiness over the body, especially the legs.

by that definition, but fentanyl and buprenorphine are not. It does have activity at the mu opiate receptor, but the activity is very different from that of agonists like methadone, oxycodone, or fentanyl. Buprenorphine is a partial agonist, which causes tolerance that is static, rather than the ever-increasing tolerance caused by agonists. It also has a 'ceiling' to it's agonist effect.

just came across this thread. I started the patch journey about 6 month ago. Started on Butrans and transtec......didn't hit the spot (severe pelvic and abdominal adhesions cause my pain). Moved onto Fentanly. 50mg I have turned into Satan! Anger, moods, hatred - got im an absolute b*tch! Decided I needed to get off this crap.....

Hi Phillin: I'm sorry to hear that the Fentanyl is causing you troubles. Your Doctor is correct. It sounds as if your Metabolism is in high gear and in your case need to change the patch more often. I too use Fentanyl. I am on 100mcg every 48hrs. I couldn't go the 72hr. and it wasn't because I felt weird or uncomfortable in my skin. I was in added pain by the third day and needed to change the patch more often.

Fentanyl is the only opioid stronger than buprenorphine and is difficult to determine equivalents. Methadone and all the synthetic opioids seem to have a different affect on everyone. Technically, legally, officially there is no accepted standard of converting methadone to other opioids. Most conversions are based on morohine equivalents, but what I found was approx .36 mcg fentanyl to 40 Mgs of methadone.

The 3 a day didn't last long and went back to 4 a day and have now decided to try cold turkey and so have stopped from today with the Actiq. I still have the Fentanyl 50 patch. I hope I can manage as I have decided to go on a short holiday to distract myself.

Been on Subutex for chronic pain control since I went to rehab to beat a Fentanyl/Roxycodone/Oxycontin addiction in July 2009., For anyone who has wondered about this, it really works well. The thing about it is that for people like us who are used to getting all those lovely opiate side effects, you don't get those with Subutex (there's a mild euphoria when you take the pill under your tongue, but that passes within a half hour).

I suffer from severe endometriosis and have been taking 30/500 cocodamol 10 plus a day and tramadol 50mg 8 a day together for 18 months plus and have now been put on BuTrans Transdermal patch Buprenorphine 5mg/hr per week, i put one on monday at 5.30 and now its 8pm thursday and have had no relief what so ever i've applied a second patch at 6.

However, it was reported in another study that ketoconazole increased the Cmax and AUC of buprenorphine (route unspecified) by approximately 70% and 50%, respectively, and to a lesser extent, of the metabolite norbuprenorphine. The interaction has also been reported with atazanavir/ritonavir.

I am currently using 8mg of buprenorphine,1800mg of gabapentin and 150mg of wellbutrin daily as medicine for pain management and nerve pain.Now I'cant obtain gabapentin anymore and would like to transfer to oxycodone 120mg daily as a substitute for buprenorphine and gabapentin.I would like to know is such change possible.

I am 26 years old and I have had a problem with addiction for some time now. To make a long story short I have always had problems with my back so I started taking pain pills then pain pills stopped working and unfortunatley I started taking suboxone. I have been taking suboxone for a year and 4 months and I buy it from a friend bc I have no insurance.

Subutex® is a single entity buprenorphine product and Suboxone® is a combination product with buprenorphine and naloxone in a 4:1 ratio, respectively. After reviewing all the available data and receiving a schedule III recommendation from the Department of Health and Human Services (DHHS), the DEA placed buprenorphine and all products containing buprenorphine into schedule III in 2002. Since 2003, diversion, trafficking and abuse of buprenorphine have become more common in the United States.

In addition, some of these inducers (anticonvulsants and barbiturates) may have additive central nervous system-depressant effects with buprenorphine. MANAGEMENT: Pharmacologic response to buprenorphine should be monitored more closely whenever a CYP450 3A4 inducer is added to or withdrawn from therapy, and the buprenorphine dosage adjusted as necessary. Ambulatory patients should be made aware of the possibility of additive effects (e.g.

Buprenorphine is a thebaine derivative with powerful analgesia approximately 20-40x more potent than morphine. Buprenorphine is a partial agonist and antagonist of the opioid receptors in the central nervous system which means that when its molecule binds to a receptor, it will transduce only a partial response in contrast to a full agonist such as morphine. Buprenorphine also has very high binding to the opioid receptors such that the opioid receptor antagonists (e.g.

Fentanyl and buprenorphine

Common Questions and Answers about Fentanyl and buprenorphine

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